Neuroprotective effects of an Nrf2 agonist on high glucose-induced damage in HT22 cells
Abstract Background: Oxidative stress is the hallmark of diabetic encephalopathy, which may be caused by hyperglycaemic toxicity. We aimed to discover pharmacologic targets to restore redox homeostasis. We identified the transcription factor Nrf2 as such a target. Methods: HT22 cells were cultured...
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Autores principales: | , , , , , , , |
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Lenguaje: | English |
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Sociedad de Biología de Chile
2019
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Materias: | |
Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602019000100249 |
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