Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells

Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells

Abstract Background: Mast cells (MCs) have been found to play a critical role during development of inflammatory bowel disease (IBD) that characterized by dysregulation of inflammation and impaired intestinal barrier function. However, the function of MCs in IBD remains to be fully elucidated. Res...

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Autores principales: Li,Musheng, Zhao,Junhong, Cao,Meiwan, Liu,Ruitao, Chen,Guanhua, Li,Songyu, Xie,Yuanwen, Xie,Jing, Cheng,Yang, Huang,Ling, Su,Mingmin, Xu,Yuxin, Zheng,Mingyue, Zou,Kejian, Geng,Lanlan, Xu,Wanfu, Gong,Sitang
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2020
Materias:
Mast cells
Exosomes
miR-223
Claudin 8
Inflammatory bowel disease
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602020000100210
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