DNA removal from a purification process of recombinant hepatitis B surface antigen
We studied the capacity of an API-rHBsAg purification process to eliminate DNA contamination from yeast-host cell. Firstly, was demonstrated consistency of manufacturing purification process to remove DNA, from (3.9 ± 1.9)10(8) pg/dose in starting material to (3.4 ± 1.6) pg/dose, equivalent to 8.2 l...
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| Autores principales: | , , , , , |
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| Lenguaje: | Spanish / Castilian |
| Publicado: |
Pontificia Universidad Católica de Valparaíso
2007
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| Materias: | |
| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582007000100004 |
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