Can painting human cells with exogenous maltoporin enable efficient therapeutic gene transfer by bacteriophage lambda vectors?

Many gene therapy strategies require transfer of high-molecular weight DNA into human cells. To enable clinical trials, these vectors need to be produced on a large scale and at low cost. The production of effective high-capacity vectors like HSV-amplicons and helper-dependent adenoviral vectors is...

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Autor principal: Tolmachov,Oleg
Lenguaje:English
Publicado: Pontificia Universidad Católica de Valparaíso 2009
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582009000400012
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