High-yield production of the human lysozyme by Pichia pastoris SMD1168 using response surface methodology and high-cell-density fermentation

Background Lysozyme plays a crucial role in innate immunity with its well-recognized bacteriolytic activity. In this study, the influence of expression parameters (inoculation volume, culture volume, growth time, induction temperature and time, initial pH and methanol concentration) on human lysozym...

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Bibliographic Details
Main Authors: Yu,Ying, Zhou,Xiaoyu, Wu,Sheng, Wei,Tiantian, Yu,Long
Language:English
Published: Pontificia Universidad Católica de Valparaíso 2014
Subjects:
LYZ
RSM
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582014000600009
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