High-yield production of the human lysozyme by Pichia pastoris SMD1168 using response surface methodology and high-cell-density fermentation
Background Lysozyme plays a crucial role in innate immunity with its well-recognized bacteriolytic activity. In this study, the influence of expression parameters (inoculation volume, culture volume, growth time, induction temperature and time, initial pH and methanol concentration) on human lysozym...
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Autores principales: | , , , , |
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Lenguaje: | English |
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Pontificia Universidad Católica de Valparaíso
2014
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Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582014000600009 |
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