Effect of cheese containing Lactobacillus delbrueckii subsp. Lactis CRL 581 on blood pressure in prehypertensive and stage 1 hypertensive subjects

ABSTRACT Hypertension is one of the main risk factors for cardiovascular disease. Functional foods containing bioactive peptides have been proposed as a strategy to decrease blood pressure (BP) in subjects under no pharmacological treatment. The aim of this study was to compare the effect of low-sod...

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Autores principales:	Salazar,Martín, Malpeli,Agustina, Hebert,Elvira, Cravero,Ricardo, Espeche,Walter, Sisnieguez,Cecilia Leiva, Stavile,Rodolfo N., March,Carlos, Sisnieguez,Carlos Leiva, Tavella,Marina, Disalvo,Liliana, Fasano,Victoria, Magrini,Graciano, Visentin,Dimas, Taranto,M. Pía, González,Horacio F.
Lenguaje:	English
Publicado:	Sociedad Chilena de Nutrición, Bromatología y Toxicología 2019
Materias:	Biopeptides Cheese Functional foods Lactobacillus delbrueckii Pre-hypertension
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182019000600701
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spelling	oai:scielo:S0717-751820190006007012020-03-24Effect of cheese containing Lactobacillus delbrueckii subsp. Lactis CRL 581 on blood pressure in prehypertensive and stage 1 hypertensive subjectsSalazar,MartínMalpeli,AgustinaHebert,ElviraCravero,RicardoEspeche,WalterSisnieguez,Cecilia LeivaStavile,Rodolfo N.March,CarlosSisnieguez,Carlos LeivaTavella,MarinaDisalvo,LilianaFasano,VictoriaMagrini,GracianoVisentin,DimasTaranto,M. PíaGonzález,Horacio F. Biopeptides Cheese Functional foods Lactobacillus delbrueckii Pre-hypertension ABSTRACT Hypertension is one of the main risk factors for cardiovascular disease. Functional foods containing bioactive peptides have been proposed as a strategy to decrease blood pressure (BP) in subjects under no pharmacological treatment. The aim of this study was to compare the effect of low-sodium, low-fat (LSLF) cheese and LSLF cheese containing Lactobacillus delbrueckii subsp. lactis CRL 581 (LSLF581) on BP in pre-hypertensive and stage 1 hypertensive subjects. Sixty-one pre-hypertensive and stage 1 hypertensive subjects assigned to one of twos (LSLF, n= 29 and LSLF581, n= 32) participated in this 12-month prospective, randomized, double-blind, crossover trial. Twenty-four h ambulatory BP monitoring was performed at the beginning and at the end of each four-week study period. Systolic and diastolic BP decreased in both study groups, but differences between groups were not significant (systolic, −1.78 and −0.2 mmHg; diastolic, −1.54 and −0.42 mmHg in LSLF581 and LSLF, respectively). Although our results could not support a BP lowering effect of LSLF581, small BP reductions could favorably prevent cardiovascular disease development.info:eu-repo/semantics/openAccessSociedad Chilena de Nutrición, Bromatología y ToxicologíaRevista chilena de nutrición v.46 n.6 20192019-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182019000600701en10.4067/S0717-75182019000600701
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Biopeptides Cheese Functional foods Lactobacillus delbrueckii Pre-hypertension
spellingShingle	Biopeptides Cheese Functional foods Lactobacillus delbrueckii Pre-hypertension Salazar,Martín Malpeli,Agustina Hebert,Elvira Cravero,Ricardo Espeche,Walter Sisnieguez,Cecilia Leiva Stavile,Rodolfo N. March,Carlos Sisnieguez,Carlos Leiva Tavella,Marina Disalvo,Liliana Fasano,Victoria Magrini,Graciano Visentin,Dimas Taranto,M. Pía González,Horacio F. Effect of cheese containing Lactobacillus delbrueckii subsp. Lactis CRL 581 on blood pressure in prehypertensive and stage 1 hypertensive subjects
description	ABSTRACT Hypertension is one of the main risk factors for cardiovascular disease. Functional foods containing bioactive peptides have been proposed as a strategy to decrease blood pressure (BP) in subjects under no pharmacological treatment. The aim of this study was to compare the effect of low-sodium, low-fat (LSLF) cheese and LSLF cheese containing Lactobacillus delbrueckii subsp. lactis CRL 581 (LSLF581) on BP in pre-hypertensive and stage 1 hypertensive subjects. Sixty-one pre-hypertensive and stage 1 hypertensive subjects assigned to one of twos (LSLF, n= 29 and LSLF581, n= 32) participated in this 12-month prospective, randomized, double-blind, crossover trial. Twenty-four h ambulatory BP monitoring was performed at the beginning and at the end of each four-week study period. Systolic and diastolic BP decreased in both study groups, but differences between groups were not significant (systolic, −1.78 and −0.2 mmHg; diastolic, −1.54 and −0.42 mmHg in LSLF581 and LSLF, respectively). Although our results could not support a BP lowering effect of LSLF581, small BP reductions could favorably prevent cardiovascular disease development.
author	Salazar,Martín Malpeli,Agustina Hebert,Elvira Cravero,Ricardo Espeche,Walter Sisnieguez,Cecilia Leiva Stavile,Rodolfo N. March,Carlos Sisnieguez,Carlos Leiva Tavella,Marina Disalvo,Liliana Fasano,Victoria Magrini,Graciano Visentin,Dimas Taranto,M. Pía González,Horacio F.
author_facet	Salazar,Martín Malpeli,Agustina Hebert,Elvira Cravero,Ricardo Espeche,Walter Sisnieguez,Cecilia Leiva Stavile,Rodolfo N. March,Carlos Sisnieguez,Carlos Leiva Tavella,Marina Disalvo,Liliana Fasano,Victoria Magrini,Graciano Visentin,Dimas Taranto,M. Pía González,Horacio F.
author_sort	Salazar,Martín
title	Effect of cheese containing Lactobacillus delbrueckii subsp. Lactis CRL 581 on blood pressure in prehypertensive and stage 1 hypertensive subjects
title_short	Effect of cheese containing Lactobacillus delbrueckii subsp. Lactis CRL 581 on blood pressure in prehypertensive and stage 1 hypertensive subjects
title_full	Effect of cheese containing Lactobacillus delbrueckii subsp. Lactis CRL 581 on blood pressure in prehypertensive and stage 1 hypertensive subjects
title_fullStr	Effect of cheese containing Lactobacillus delbrueckii subsp. Lactis CRL 581 on blood pressure in prehypertensive and stage 1 hypertensive subjects
title_full_unstemmed	Effect of cheese containing Lactobacillus delbrueckii subsp. Lactis CRL 581 on blood pressure in prehypertensive and stage 1 hypertensive subjects
title_sort	effect of cheese containing lactobacillus delbrueckii subsp. lactis crl 581 on blood pressure in prehypertensive and stage 1 hypertensive subjects
publisher	Sociedad Chilena de Nutrición, Bromatología y Toxicología
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182019000600701
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Effect of cheese containing Lactobacillus delbrueckii subsp. Lactis CRL 581 on blood pressure in prehypertensive and stage 1 hypertensive subjects

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