Morphometric Analysis and Pattern of Protein and Gene Expression of Apoptosis in Focal Cerebral Ischemia in Rats and the Neuroprotetive Action of Hypothermia and Ketoprofen

Morphometric Analysis and Pattern of Protein and Gene Expression of Apoptosis in Focal Cerebral Ischemia in Rats and the Neuroprotetive Action of Hypothermia and Ketoprofen

SUMMARY: This study aimed to investigate the morphometric and the pattern of protein and gene expression related to the extrinsic apoptotic pathway in experimental focal cerebral ischemia and the hole of neuroprotection with hypothermia and ketoprofen. For this analysis, 120 rats were randomly divid...

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Autores principales: Tirapelli,Daniela P. C, Cirino,Mucio Luiz de Assis, Carvalho,Camila A. Melo de, Novais,Paulo Cezar, Figueredo,Rafael Zimak, Porsani,Lucas Barbosa, Gula,Isabella Stracieri, Rodrigues,Andressa Romualdo, Silva,Jairo Pinheiro da, Pereira,Adriana Lis, Lizarte Neto,Fermino Sanches, Schimming,Bruno Cesar, Tazima,Maria de Fátima Galli Sorita, Fazan,Valéria de Paula Sassoli, Carlotti-Jr,Carlos Gilberto, Tirapelli,Luis Fernando, Colli,Benedicto Oscar
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2020
Materias:
Apoptosis
Gene expression
Caspase-3
Cerebral ischemia
Neuroprotection
Hypothermia
Ketoprofen
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000300523
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