ASSESSMENT OF THE HYDROLYTIC DEGRADATION OF LOVASTATIN BY HPLC
In this work an HPLC stability-indicating method was developed and applied to study the hydrolytic behaviour of lovastatin in different simulated fluids. The selected chromatographic conditions were a C-18 column, acetonitrile/methanol/phosphate buffer solution pH 4 (32/33/35) as mobile phase, 45ºC...
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| Auteurs principaux: | , , , |
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| Langue: | English |
| Publié: |
Sociedad Chilena de Química
2005
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| Accès en ligne: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072005000400002 |
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