ASSESSMENT OF THE HYDROLYTIC DEGRADATION OF LOVASTATIN BY HPLC
In this work an HPLC stability-indicating method was developed and applied to study the hydrolytic behaviour of lovastatin in different simulated fluids. The selected chromatographic conditions were a C-18 column, acetonitrile/methanol/phosphate buffer solution pH 4 (32/33/35) as mobile phase, 45ºC...
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Autores principales: | ÁLVAREZ-LUEJE,A, PASTINE,J, SQUELLA,J.A, NUÑEZ-VERGARA,L.J |
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Lenguaje: | English |
Publicado: |
Sociedad Chilena de Química
2005
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Materias: | |
Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072005000400002 |
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