ANTIOXIDANT ACTIVITY OF FLAVONOIDS ISOLATED FROM HYPERICUM TERNUM

In the present work we have studied the scavenging activity of several flavonoids isolated from Hypericum ternum A. St. Hil. The evaluation of the free radical scavenging capacity was based on the 2,2-diphenyl-l-picrylhydrazyl radical (DPPH) consumption elicited by their addition. Also, we have atte...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	BERNARDI,A.P.M, LÓPEZ-ALARCÓN,C, ASPEE,A, RECH,S, VON POSER,G.L, BRIDE,R, LISSP,E
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2007
Materias:	Hypericum ternum antioxidant activity flavonoids
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072007000400013
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0717-97072007000400013
record_format	dspace
spelling	oai:scielo:S0717-970720070004000132008-04-30ANTIOXIDANT ACTIVITY OF FLAVONOIDS ISOLATED FROM HYPERICUM TERNUMBERNARDI,A.P.MLÓPEZ-ALARCÓN,CASPEE,ARECH,SVON POSER,G.LBRIDE,RLISSP,E Hypericum ternum antioxidant activity flavonoids In the present work we have studied the scavenging activity of several flavonoids isolated from Hypericum ternum A. St. Hil. The evaluation of the free radical scavenging capacity was based on the 2,2-diphenyl-l-picrylhydrazyl radical (DPPH) consumption elicited by their addition. Also, we have attempted to evaluate their capacity to delay pyrogallol red consumption promoted by peroxyl radicals. The compounds isolated and characterized were 13,118-biapigenin and five quercetin derivatives (quercetin 3-methyl ether, quercetin 3,7-dimethyl ether, hyperoside, isoquercitrin and guaijaverin). All compounds were able to scavenge DPPH radicals. The order in scavenging capacity (from highest to lowest) was: guaijaverin > hyperoside ≈ isoquercitrin > quercetin-3-methyl-ether. No protection of pyrogallol red was evidenced for all flavonoids derivatives at relatively high (100 µM) concentrations. This lack of protection contrasts with the efficient protection afforded by 10 µM quercetin, indicating that substitution at the 3-position in quercetin strongly reduces the capacity of the molecule to scavenge peroxyl radicalsinfo:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.52 n.4 20072007-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072007000400013en10.4067/S0717-97072007000400013
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Hypericum ternum antioxidant activity flavonoids
spellingShingle	Hypericum ternum antioxidant activity flavonoids BERNARDI,A.P.M LÓPEZ-ALARCÓN,C ASPEE,A RECH,S VON POSER,G.L BRIDE,R LISSP,E ANTIOXIDANT ACTIVITY OF FLAVONOIDS ISOLATED FROM HYPERICUM TERNUM
description	In the present work we have studied the scavenging activity of several flavonoids isolated from Hypericum ternum A. St. Hil. The evaluation of the free radical scavenging capacity was based on the 2,2-diphenyl-l-picrylhydrazyl radical (DPPH) consumption elicited by their addition. Also, we have attempted to evaluate their capacity to delay pyrogallol red consumption promoted by peroxyl radicals. The compounds isolated and characterized were 13,118-biapigenin and five quercetin derivatives (quercetin 3-methyl ether, quercetin 3,7-dimethyl ether, hyperoside, isoquercitrin and guaijaverin). All compounds were able to scavenge DPPH radicals. The order in scavenging capacity (from highest to lowest) was: guaijaverin > hyperoside ≈ isoquercitrin > quercetin-3-methyl-ether. No protection of pyrogallol red was evidenced for all flavonoids derivatives at relatively high (100 µM) concentrations. This lack of protection contrasts with the efficient protection afforded by 10 µM quercetin, indicating that substitution at the 3-position in quercetin strongly reduces the capacity of the molecule to scavenge peroxyl radicals
author	BERNARDI,A.P.M LÓPEZ-ALARCÓN,C ASPEE,A RECH,S VON POSER,G.L BRIDE,R LISSP,E
author_facet	BERNARDI,A.P.M LÓPEZ-ALARCÓN,C ASPEE,A RECH,S VON POSER,G.L BRIDE,R LISSP,E
author_sort	BERNARDI,A.P.M
title	ANTIOXIDANT ACTIVITY OF FLAVONOIDS ISOLATED FROM HYPERICUM TERNUM
title_short	ANTIOXIDANT ACTIVITY OF FLAVONOIDS ISOLATED FROM HYPERICUM TERNUM
title_full	ANTIOXIDANT ACTIVITY OF FLAVONOIDS ISOLATED FROM HYPERICUM TERNUM
title_fullStr	ANTIOXIDANT ACTIVITY OF FLAVONOIDS ISOLATED FROM HYPERICUM TERNUM
title_full_unstemmed	ANTIOXIDANT ACTIVITY OF FLAVONOIDS ISOLATED FROM HYPERICUM TERNUM
title_sort	antioxidant activity of flavonoids isolated from hypericum ternum
publisher	Sociedad Chilena de Química
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072007000400013
work_keys_str_mv	AT bernardiapm antioxidantactivityofflavonoidsisolatedfromhypericumternum AT lopezalarconc antioxidantactivityofflavonoidsisolatedfromhypericumternum AT aspeea antioxidantactivityofflavonoidsisolatedfromhypericumternum AT rechs antioxidantactivityofflavonoidsisolatedfromhypericumternum AT vonposergl antioxidantactivityofflavonoidsisolatedfromhypericumternum AT brider antioxidantactivityofflavonoidsisolatedfromhypericumternum AT lisspe antioxidantactivityofflavonoidsisolatedfromhypericumternum
_version_	1718445379629875200

ANTIOXIDANT ACTIVITY OF FLAVONOIDS ISOLATED FROM HYPERICUM TERNUM

Ejemplares similares