DEVELOPMENT AND VALIDATION OF LIQUID CHROMATOGRAPHIC METHOD FOR GEMFIBROZIL AND SIMVASTATIN IN BINARY COMBINATION

A simple, sensitive and validated HPLC method has been developed to determine gemfibrozil and simvastatin simultaneously in synthetic mixture form. Chromatographic separation was achieved on a C-18 column using a mixture of 0.1 M ammonium acétate pH 5.0 and acetonitrile in the ratio of 15:85 (v/v) a...

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Autores principales: ASHFAQ,MUHAMMAD, ULLAH KHAN,ISLAM, NADEEM ASGHAR,MUHAMMAD
Lenguaje:English
Publicado: Sociedad Chilena de Química 2008
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072008000300015
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