IN VITRO EVIDENCES FOR SIMVASTATIN AND LOSARTAN POTASSIUM INTERACTION AND ITS IN VIVO IMPLICATIONS
In the present paper, we describe the in vitro availability of simvastatin, a potent HMG-CoA reductase inhibitor, in presence of losartan potassium, which is a non-peptide angiotensin II receptor antagonist. These studies were carried out at 37, 48 and 60°C in different pH environments simulating hu...
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| Auteurs principaux: | , , , |
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| Langue: | English |
| Publié: |
Sociedad Chilena de Química
2009
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| Accès en ligne: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000400024 |
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