SECONDARY METABOLITES ISOLATED FROM THE FUNGUS MONASCUS KAOLIANG-FERMENTED RICE

SECONDARY METABOLITES ISOLATED FROM THE FUNGUS MONASCUS KAOLIANG-FERMENTED RICE

A chemical study of the EtOAc-soluble ethanolic extract of Monascus kaoliang BCRC 31506 (Eurotiaceae) fermented rice led to the isolation of a new furan-3-one derivative along with 9 known compounds, monascin (2), ankaflavin (3), N-trans-feruloyltyramine (4), vanillic acid (5), 4-acetonyl-3,5-dimeth...

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Main Authors: CHENG,MING-JEN, WU,MING-DER, YANG,PING-SHIN, CHEN,JIH-JUNG, CHEN,IH-SHENG, CHEN,YEN-LIN, YUAN,GWO-FANG
Language:English
Published: Sociedad Chilena de Química 2010
Subjects:
Monascus kaoliang
fungus
fermented Rice (red mold rice)
furan derivative
monascuskaoliaone
DPPH
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000100025
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Summary:A chemical study of the EtOAc-soluble ethanolic extract of Monascus kaoliang BCRC 31506 (Eurotiaceae) fermented rice led to the isolation of a new furan-3-one derivative along with 9 known compounds, monascin (2), ankaflavin (3), N-trans-feruloyltyramine (4), vanillic acid (5), 4-acetonyl-3,5-dimethoxy-p-quinol (6), (+)-ß-eudesmol (7), trans-phytol (8), aesculetin dimethyl ether (9) and (-)-matairesinol (10). Structure 1 is proposed for monascuskaoliaone on the basis of spectroscopic evidence (NMR, UV, IR, and HRMS). None of the compounds exhibited significant scavenging activity toward DPPH radical in bioautography or spectroscopic assays.

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