A DFT STUDY OF THE RELATIONSHIPS BETWEEN ELECTRONIC STRUCTURE AND PERIPHERAL BENZODIAZEPINE RECEPTOR AFFINITY IN A GROUP OF N,N-DIALKYL-2-PHENYLINDOL-3-YLGLYOXYLAMIDES

A DFT STUDY OF THE RELATIONSHIPS BETWEEN ELECTRONIC STRUCTURE AND PERIPHERAL BENZODIAZEPINE RECEPTOR AFFINITY IN A GROUP OF N,N-DIALKYL-2-PHENYLINDOL-3-YLGLYOXYLAMIDES

We present here the results of a Density Functional Theory study of the relationships between electronic structure and peripheral benzodiazepine receptor affinity for a group of N,N-dialkyl-2-phenylindol-3-ylglyoxylamide derivatives. As expected for a receptor that evolved over many millions of year...

Description complète

Enregistré dans:
Détails bibliographiques
Auteur principal: GÓMEZ-JERIA,JUAN S
Langue:English
Publié: Sociedad Chilena de Química 2010
Sujets:
Density Functional Theory
Fukui indices
superdelocalizabilities
structure-activity relationships
receptor affinity
peripheral benzodiazepine receptor
Accès en ligne:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000300024
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000300024

Documents similaires