SYNTHESIS AND AChE INHIBITING ACTIVITY OF 2, 4 SUBSTITUTED 6-PHENYL PYRIMIDINES

Novel substituted pyrimidines were synthesized from methyl 2,4-dioxo-4-phenyl-butanoate (I-A) and urea, followed by Mitsunobu coupling of I-A with benzyl or allyl alcohol to give the corresponding 2-hydroxypyrimidine ethers in good yields. Saponification of I-A, followed by reaction with benzyl or a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: PAZ,CRISTIAN, PETER,MARTIN G, SCHMIDT,BERND, BECERRA,JOSE, GUTIÉRREZ,MARGARITA, ASTUDILLO,LUIS, SILVA,MARIO
Lenguaje:English
Publicado: Sociedad Chilena de Química 2012
Materias:
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072012000300020
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!