ENANTIOMERIC LC SEPARATION OF METOLAZONE ON AMYLOSE BASED SORBENT

A simple, rapid and robust LC method was developed and validated for the enantiomeric separation of metolazone. The enantiomers of metolazone were resolved on a Chiralpak AD-H (amylose based stationary phase) column using a mobile phase consisting of Hexane: 2-propanol: Methanol: Acetic acid (80:10:...

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Autores principales: RANE,VIPUL. P, PATIL,KIRAN. R, YEOLE,RAVINDRA. D, SHINDE,DEVANAND. B
Lenguaje:English
Publicado: Sociedad Chilena de Química 2013
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072013000100019
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