STRUCTURAL EFFECTS OF THE AU(I) DRUG AURANOFIN ON CELL MEMBRANES AND MOLECULAR MODELS

Auranofin is a gold compound that is widely used for the treatment of rheumatoid arthritis. It is a monomeric linear complex with triethylphosphine and thiolate moieties bounded to an Au(I) center. Gold compounds are well known for their neurological and nephrotoxic implications. However, haematolog...

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Autores principales: SUWALSKY,MARIO, GONZÁLEZ,RAQUEL, VILLENA,FERNANDO, BOLOGNIN,SILVIA
Lenguaje:English
Publicado: Sociedad Chilena de Química 2013
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072013000400021
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