BOX-BEHNKEN SUPPORTED DEVELOPMENT AND VALIDATION OF ROBUST RP-HPLC METHOD: AN APPLICATION IN ESTIMATION OF PRAVASTATIN IN BULK AND PHARMACEUTICAL DOSAGE FORM

Pravastatin, a natural bioactive compound inhibits cholesterol biosynthesis which is isolated from fungus by fermentation process. A rapid, sensitive and robust novel reversed phase-HPLC method with UV detection set at 238 nm was developed and validated for quantification of pravastatin in pure drug...

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Auteurs principaux: AHMAD,AJAZ, RAISH,MOHAMMAD, ALKHARFY,KHALID M, MOHSIN,KAZI, SHAKEEL,FAIYAZ
Langue:English
Publié: Sociedad Chilena de Química 2016
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Accès en ligne:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200022
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