ELECTROCHEMICAL, ESR, THEORETICAL STUDIES AND in vitro ANTI-T. cruzi ACTIVITY OF 2-ORGANOMETALLIC-5-NITRO-BENZIMIDAZOLES

ELECTROCHEMICAL, ESR, THEORETICAL STUDIES AND in vitro ANTI-T. cruzi ACTIVITY OF 2-ORGANOMETALLIC-5-NITRO-BENZIMIDAZOLES

ABSTRACT The bioorganometallic compounds 2-cyrhetrenyl-5-nitro-benzimidazole (Bzn-1) and 2-ferrocenyl-5-nitro-benzimidazole (Bzn-2) have been proposed as potential anti-Trypanosoma cruzi agents. In this regard, electrochemical, electron spin resonance and biological studies were carried out. Cyclic...

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Autores principales: Barriga-González,Germán, Olivares-Petit,Carla, Toro,Patricia M., Klahn,A. Hugo, Olea-Azar,Claudio, Maya,Juan D., Huentupil,Yosselin, Arancibia,Rodrigo
Lenguaje:English
Publicado: Sociedad Chilena de Química 2020
Materias:
Organometallic-benzimidazoles
Cyclic voltammetry
ESR
Trypanocidal activity
computational calculations
DFT
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072020000104692
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