BENZIMIDAZOLE MOLECULE HYBRID WITH OXADIAZOLE RING AS ANTIPROLIFERATIVE AGENTS: IN-SILICO ANALYSIS, SYNTHESIS AND BIOLOGICAL EVALUATION

BENZIMIDAZOLE MOLECULE HYBRID WITH OXADIAZOLE RING AS ANTIPROLIFERATIVE AGENTS: IN-SILICO ANALYSIS, SYNTHESIS AND BIOLOGICAL EVALUATION

ABSTRACT A new series of benzimidazole molecules hyride with oxadiazole ring were design with an intention to search new antiproliferative lead compound. In-Silico toxicity of lead compound was also performed by using T.E.S.T software tool, a program from US Environmental Protection Agency. Drug lik...

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Autores principales: Rashid,Mohammad, Afzal,Obaid, Altamimi,Abdulmalik Saleh Alfawaz
Lenguaje:English
Publicado: Sociedad Chilena de Química 2021
Materias:
Benzimidazole
Oxadiazole
Lipinski's rule
OSIRIS Property
Pre ADMET
T.E.S.T tool
NCI and Antiproliferative activity
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072021000205164
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