Nutrient absorption, feed intake and liveweight change as a consequence of Roux-en-Y gastric bypass with increasing alimentary limb lengths in the pig model

Roux-en Y gastric bypass (RYGBP) combines a restrictive and malabsortive component of the digestive system. Metabolic outcomes of increasing the latter, is a matter of research interest. The aim of this study was to evaluate the nutritional consequences of RYGBP with different alimentary limb length...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Gandarillas,Mónica, Boz,Camilo, Barrales,Luis, Hodgkinson,Suzanne Marie, Bas,Fernando
Lenguaje:	English
Publicado:	Pontificia Universidad Católica de Chile. Facultad de Agronomía e Ingeniería Forestal 2011
Materias:	Gastric bypass Roux-en-Y pig nutrition obesity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202011000100003
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0718-16202011000100003
record_format	dspace
spelling	oai:scielo:S0718-162020110001000032011-08-18Nutrient absorption, feed intake and liveweight change as a consequence of Roux-en-Y gastric bypass with increasing alimentary limb lengths in the pig modelGandarillas,MónicaBoz,CamiloBarrales,LuisHodgkinson,Suzanne MarieBas,Fernando Gastric bypass Roux-en-Y pig nutrition obesity Roux-en Y gastric bypass (RYGBP) combines a restrictive and malabsortive component of the digestive system. Metabolic outcomes of increasing the latter, is a matter of research interest. The aim of this study was to evaluate the nutritional consequences of RYGBP with different alimentary limb lengths using a pig model. Twenty-six pigs were randomly assigned to four laparoscopic procedures: RYGBP with 300 cm of alimentary limb (T300); RYGBP with 600 cm (T600); RYGBP with 900 cm (T900); sham operation (TS). RYGBP consisted of creating a proximal gastric pouch with a 300, 600 and 900 cm alimentary limb. Sham operation was performed by bowel transections and reanastomosis in the ileum and proximal jejunum together with gastrotomy and closure. Animals were evaluated weekly for weight increase and monthly for food intake. Eighteen weeks after surgery, fecal in vivo apparent digestibility of protein, fat, fiber, calcium and phosphorous were determined. We performed ANOVA and Tukey tests to detect differences in weight, feed intake and digestibility. We observed significant differences in liveweight after 10 weeks among T300, T600 and T900 as compared to TS. No differences were found among T300, T600 and T900. We also observed significant differences in feed intake among T300, T600 and T900 versus TS. No differences among treatments for digestibility of fat; fiber; protein and energy were found. Calcium and phosphorous apparent digestibility differed among treatments. RYGBP reduced weight increase in the porcine model and calcium and phosphorous digestibility was reduced with longer limbs.info:eu-repo/semantics/openAccessPontificia Universidad Católica de Chile. Facultad de Agronomía e Ingeniería ForestalCiencia e investigación agraria v.38 n.1 20112011-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202011000100003en10.4067/S0718-16202011000100003
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Gastric bypass Roux-en-Y pig nutrition obesity
spellingShingle	Gastric bypass Roux-en-Y pig nutrition obesity Gandarillas,Mónica Boz,Camilo Barrales,Luis Hodgkinson,Suzanne Marie Bas,Fernando Nutrient absorption, feed intake and liveweight change as a consequence of Roux-en-Y gastric bypass with increasing alimentary limb lengths in the pig model
description	Roux-en Y gastric bypass (RYGBP) combines a restrictive and malabsortive component of the digestive system. Metabolic outcomes of increasing the latter, is a matter of research interest. The aim of this study was to evaluate the nutritional consequences of RYGBP with different alimentary limb lengths using a pig model. Twenty-six pigs were randomly assigned to four laparoscopic procedures: RYGBP with 300 cm of alimentary limb (T300); RYGBP with 600 cm (T600); RYGBP with 900 cm (T900); sham operation (TS). RYGBP consisted of creating a proximal gastric pouch with a 300, 600 and 900 cm alimentary limb. Sham operation was performed by bowel transections and reanastomosis in the ileum and proximal jejunum together with gastrotomy and closure. Animals were evaluated weekly for weight increase and monthly for food intake. Eighteen weeks after surgery, fecal in vivo apparent digestibility of protein, fat, fiber, calcium and phosphorous were determined. We performed ANOVA and Tukey tests to detect differences in weight, feed intake and digestibility. We observed significant differences in liveweight after 10 weeks among T300, T600 and T900 as compared to TS. No differences were found among T300, T600 and T900. We also observed significant differences in feed intake among T300, T600 and T900 versus TS. No differences among treatments for digestibility of fat; fiber; protein and energy were found. Calcium and phosphorous apparent digestibility differed among treatments. RYGBP reduced weight increase in the porcine model and calcium and phosphorous digestibility was reduced with longer limbs.
author	Gandarillas,Mónica Boz,Camilo Barrales,Luis Hodgkinson,Suzanne Marie Bas,Fernando
author_facet	Gandarillas,Mónica Boz,Camilo Barrales,Luis Hodgkinson,Suzanne Marie Bas,Fernando
author_sort	Gandarillas,Mónica
title	Nutrient absorption, feed intake and liveweight change as a consequence of Roux-en-Y gastric bypass with increasing alimentary limb lengths in the pig model
title_short	Nutrient absorption, feed intake and liveweight change as a consequence of Roux-en-Y gastric bypass with increasing alimentary limb lengths in the pig model
title_full	Nutrient absorption, feed intake and liveweight change as a consequence of Roux-en-Y gastric bypass with increasing alimentary limb lengths in the pig model
title_fullStr	Nutrient absorption, feed intake and liveweight change as a consequence of Roux-en-Y gastric bypass with increasing alimentary limb lengths in the pig model
title_full_unstemmed	Nutrient absorption, feed intake and liveweight change as a consequence of Roux-en-Y gastric bypass with increasing alimentary limb lengths in the pig model
title_sort	nutrient absorption, feed intake and liveweight change as a consequence of roux-en-y gastric bypass with increasing alimentary limb lengths in the pig model
publisher	Pontificia Universidad Católica de Chile. Facultad de Agronomía e Ingeniería Forestal
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202011000100003
work_keys_str_mv	AT gandarillasmonica nutrientabsorptionfeedintakeandliveweightchangeasaconsequenceofrouxenygastricbypasswithincreasingalimentarylimblengthsinthepigmodel AT bozcamilo nutrientabsorptionfeedintakeandliveweightchangeasaconsequenceofrouxenygastricbypasswithincreasingalimentarylimblengthsinthepigmodel AT barralesluis nutrientabsorptionfeedintakeandliveweightchangeasaconsequenceofrouxenygastricbypasswithincreasingalimentarylimblengthsinthepigmodel AT hodgkinsonsuzannemarie nutrientabsorptionfeedintakeandliveweightchangeasaconsequenceofrouxenygastricbypasswithincreasingalimentarylimblengthsinthepigmodel AT basfernando nutrientabsorptionfeedintakeandliveweightchangeasaconsequenceofrouxenygastricbypasswithincreasingalimentarylimblengthsinthepigmodel
_version_	1714202128494362624

Nutrient absorption, feed intake and liveweight change as a consequence of Roux-en-Y gastric bypass with increasing alimentary limb lengths in the pig model

Ejemplares similares