Repression of Human Papillomavirus Oncogene Expression under Hypoxia Is Mediated by PI3K/mTORC2/AKT Signaling

por Felicitas Bossler, Bianca J. Kuhn, Thomas Günther, Stephen J. Kraemer, Prajakta Khalkar, Svenja Adrian, Claudia Lohrey, Angela Holzer, Mitsugu Shimobayashi, Matthias Dürst, Arnulf Mayer, Frank Rösl, Adam Grundhoff, Jeroen Krijgsveld, Karin Hoppe-Seyler, Felix Hoppe-Seyler
Publicado 2019

Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release

por Fei Xiao, Stanley Wang, Rina Barouch-Bentov, Gregory Neveu, Szuyuan Pu, Melanie Beer, Stanford Schor, Sathish Kumar, Vlad Nicolaescu, Brett D. Lindenbach, Glenn Randall, Shirit Einav
Publicado 2018

Polymyxin Combinations Combat <italic toggle="yes">Escherichia coli</italic> Harboring <italic toggle="yes">mcr-1</italic> and <italic toggle="yes">bla</italic>_NDM-5: Pr...

por Zackery P. Bulman, Liang Chen, Thomas J. Walsh, Michael J. Satlin, Yuli Qian, Jürgen B. Bulitta, Charles A. Peloquin, Patricia N. Holden, Roger L. Nation, Jian Li, Barry N. Kreiswirth, Brian T. Tsuji
Publicado 2017

The Complex Quorum Sensing Circuitry of <italic toggle="yes">Burkholderia thailandensis</italic> Is Both Hierarchically and Homeostatically Organized

por Servane Le Guillouzer, Marie-Christine Groleau, Eric Déziel
Publicado 2017

<italic toggle="yes">Mycobacterium tuberculosis</italic> PhoY Proteins Promote Persister Formation by Mediating Pst/SenX3-RegX3 Phosphate Sensing

por Sarah B. Namugenyi, Alisha M. Aagesen, Sarah R. Elliott, Anna D. Tischler
Publicado 2017

The New Xpert MTB/RIF Ultra: Improving Detection of <italic toggle="yes">Mycobacterium tuberculosis</italic> and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testi...

por Soumitesh Chakravorty, Ann Marie Simmons, Mazhgan Rowneki, Heta Parmar, Yuan Cao, Jamie Ryan, Padmapriya P. Banada, Srinidhi Deshpande, Shubhada Shenai, Alexander Gall, Jennifer Glass, Barry Krieswirth, Samuel G. Schumacher, Pamela Nabeta, Nestani Tukvadze, Camilla Rodrigues, Alena Skrahina, Elisa Tagliani, Daniela M. Cirillo, Amy Davidow, Claudia M. Denkinger, David Persing, Robert Kwiatkowski, Martin Jones, David Alland
Publicado 2017

Comparative Genomic Analysis of Globally Dominant ST131 Clone with Other Epidemiologically Successful Extraintestinal Pathogenic <italic toggle="yes">Escherichia coli</italic> (ExP...

por Sabiha Shaik, Amit Ranjan, Sumeet K. Tiwari, Arif Hussain, Nishant Nandanwar, Narender Kumar, Savita Jadhav, Torsten Semmler, Ramani Baddam, Mohammed Aminul Islam, Munirul Alam, Lothar H. Wieler, Haruo Watanabe, Niyaz Ahmed
Publicado 2017

Target Mechanism-Based Whole-Cell Screening Identifies Bortezomib as an Inhibitor of Caseinolytic Protease in Mycobacteria

por Wilfried Moreira, Grace J. Y. Ngan, Jian Liang Low, Anders Poulsen, Brian C. S. Chia, Melgious J. Y. Ang, Amelia Yap, Justina Fulwood, Umayal Lakshmanan, Jolander Lim, Audrey Y. T. Khoo, Horst Flotow, Jeffrey Hill, Ravikiran M. Raju, Eric J. Rubin, Thomas Dick
Publicado 2015

Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection

por Laxmi Yeruva, Garry S. A. Myers, Nicole Spencer, Heather Huot Creasy, Nancy E. Adams, Anthony T. Maurelli, Grant R. McChesney, Mario A. Cleves, Jacques Ravel, Anne Bowlin, Roger G. Rank
Publicado 2014

<named-content content-type="genus-species">Aspergillus fumigatus</named-content> Transcription Factors Involved in the Caspofungin Paradoxical Effect

por Clara Valero, Ana Cristina Colabardini, Jéssica Chiaratto, Lakhansing Pardeshi, Patrícia Alves de Castro, Jaire Alves Ferreira Filho, Lilian Pereira Silva, Marina Campos Rocha, Iran Malavazi, Jonas Henrique Costa, Taícia Fill, Mário Henrique Barros, Sarah Sze Wah Wong, Vishukumar Aimanianda, Koon Ho Wong, Gustavo H. Goldman
Publicado 2020

Antiviral Efficacies of FDA-Approved Drugs against SARS-CoV-2 Infection in Ferrets

por Su-Jin Park, Kwang-Min Yu, Young-Il Kim, Se-Mi Kim, Eun-Ha Kim, Seong-Gyu Kim, Eun Ji Kim, Mark Anthony B. Casel, Rare Rollon, Seung-Gyu Jang, Min-Hyeok Lee, Jae-Hyung Chang, Min-Suk Song, Hye Won Jeong, Younho Choi, Weiqiang Chen, Woo-Jin Shin, Jae U. Jung, Young Ki Choi
Publicado 2020

Stapled Peptides Based on Human Angiotensin-Converting Enzyme 2 (ACE2) Potently Inhibit SARS-CoV-2 Infection <italic toggle="yes">In Vitro</italic>

por Francesca Curreli, Sofia M. B. Victor, Shahad Ahmed, Aleksandra Drelich, Xiaohe Tong, Chien-Te K. Tseng, Christopher D. Hillyer, Asim K. Debnath
Publicado 2020

A Role for Tetracycline Selection in Recent Evolution of Agriculture-Associated <italic toggle="yes">Clostridium difficile</italic> PCR Ribotype 078

por Kate E. Dingle, Xavier Didelot, T. Phuong Quan, David W. Eyre, Nicole Stoesser, Charis A. Marwick, John Coia, Derek Brown, Sarah Buchanan, Umer Z. Ijaz, Cosmika Goswami, Gill Douce, Warren N. Fawley, Mark H. Wilcox, Timothy E. A. Peto, A. Sarah Walker, Derrick W. Crook
Publicado 2019

Distinct Cytokine Profiles Correlate with Disease Severity and Outcome in Longitudinal Studies of Acute Hepatitis B Virus and Hepatitis D Virus Infection in Chimpanzees

por Ronald E. Engle, Davide De Battista, Emily J. Danoff, Hanh Nguyen, Zhaochun Chen, Paolo Lusso, Robert H. Purcell, Patrizia Farci
Publicado 2020

Posttranscriptional Regulation of HIV-1 Gene Expression during Replication and Reactivation from Latency by Nuclear Matrix Protein MATR3

por Ambra Sarracino, Lavina Gharu, Anna Kula, Alexander O. Pasternak, Veronique Avettand-Fenoel, Christine Rouzioux, Maryana Bardina, Stéphane De Wit, Monsef Benkirane, Ben Berkhout, Carine Van Lint, Alessandro Marcello
Publicado 2018

ACBD3 Is an Essential Pan-enterovirus Host Factor That Mediates the Interaction between Viral 3A Protein and Cellular Protein PI4KB

por Heyrhyoung Lyoo, Hilde M. van der Schaar, Cristina M. Dorobantu, Huib H. Rabouw, Jeroen R. P. M. Strating, Frank J. M. van Kuppeveld
Publicado 2019

Reprogramming of Small Noncoding RNA Populations in Peripheral Blood Reveals Host Biomarkers for Latent and Active <named-content content-type="genus-species">Mycobacterium tubercu...

por Leonardo Silva de Araujo, Marcelo Ribeiro-Alves, Thyago Leal-Calvo, Janaína Leung, Verónica Durán, Mohamed Samir, Steven Talbot, Aravind Tallam, Fernanda Carvalho de Queiroz Mello, Robert Geffers, Maria Helena Féres Saad, Frank Pessler
Publicado 2019

Dengue Virus NS Proteins Inhibit RIG-I/MAVS Signaling by Blocking TBK1/IRF3 Phosphorylation: Dengue Virus Serotype 1 NS4A Is a Unique Interferon-Regulating Virulence Determinant

por Nadine A. Dalrymple, Velasco Cimica, Erich R. Mackow
Publicado 2015

Divergent Simian Arteriviruses Cause Simian Hemorrhagic Fever of Differing Severities in Macaques

por Victoria Wahl-Jensen, Joshua C. Johnson, Michael Lauck, Jason T. Weinfurter, Louise H. Moncla, Andrea M. Weiler, Olivia Charlier, Oscar Rojas, Russell Byrum, Dan R. Ragland, Louis Huzella, Erika Zommer, Melanie Cohen, John G. Bernbaum, Yíngyún Caì, Hannah B. Sanford, Steven Mazur, Reed F. Johnson, Jing Qin, Gustavo F. Palacios, Adam L. Bailey, Peter B. Jahrling, Tony L. Goldberg, David H. O’Connor, Thomas C. Friedrich, Jens H. Kuhn
Publicado 2016

The Adenovirus E4-ORF3 Protein Stimulates SUMOylation of General Transcription Factor TFII-I to Direct Proteasomal Degradation

por Rebecca G. Bridges, Sook-Young Sohn, Jordan Wright, Keith N. Leppard, Patrick Hearing
Publicado 2016