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22781por Dharmendra Dingar, William B. Tu, Diana Resetca, Corey Lourenco, Aaliya Tamachi, Jason De Melo, Kathleen E. Houlahan, Manpreet Kalkat, Pak-Kei Chan, Paul C. Boutros, Brian Raught, Linda Z. Penn“...Deregulated MYC activity is oncogenic and is deregulated in a large fraction of human cancers. Here...”
Publicado 2018
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22782por Ying-Bei Chen, Jianing Xu, Anders Jacobsen Skanderup, Yiyu Dong, A. Rose Brannon, Lu Wang, Helen H. Won, Patricia I. Wang, Gouri J. Nanjangud, Achim A. Jungbluth, Wei Li, Virginia Ojeda, A. Ari Hakimi, Martin H. Voss, Nikolaus Schultz, Robert J. Motzer, Paul Russo, Emily H. Cheng, Filippo G. Giancotti, William Lee, Michael F. Berger, Satish K. Tickoo, Victor E. Reuter, James J. Hsieh“..., the authors examine this group of unclassified renal cancers using genomics techniques and identify further...”
Publicado 2016
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22783por Timothy P. Lippert, Paulina Marzec, Aurora I. Idilli, Grzegorz Sarek, Aleksandra Vancevska, Mark Bower, Paul J. Farrell, Päivi M. Ojala, Niklas Feldhahn, Simon J. Boulton“...~15% of cancers induce alternative lengthening of telomeres (ALT) to activate telomere maintenance...”
Publicado 2021
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22784por Cristina Ribeiro-Silva, Özge Z. Aydin, Raquel Mesquita-Ribeiro, Jana Slyskova, Angela Helfricht, Jurgen A. Marteijn, Jan H. J. Hoeijmakers, Hannes Lans, Wim Vermeulen“...SWI/SNF genes are commonly found to be mutated in different cancers. Here the authors report...”
Publicado 2018
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22785por Xianyue Ren, Xiaojing Yang, Bin Cheng, Xiaozhong Chen, Tianpeng Zhang, Qingmei He, Bin Li, Yingqin Li, Xinran Tang, Xin Wen, Qian Zhong, Tiebang Kang, Musheng Zeng, Na Liu, Jun Ma“...HOPX is a transcription factor epigenetically silenced in several cancers. Here the authors...”
Publicado 2017
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22786por Grace R. Anderson, Suzanne E. Wardell, Merve Cakir, Catherine Yip, Yeong-ran Ahn, Moiez Ali, Alexander P. Yllanes, Christina A. Chao, Donald P. McDonnell, Kris C. Wood“... mitochondrial dynamics are frequently amplified in human cancers, and that these alterations are associated...”
Publicado 2018
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22787por Bryan C. Nikolai, Prashi Jain, David L. Cardenas, Brian York, Qin Feng, Neil J. McKenna, Subhamoy Dasgupta, David M. Lonard, Bert W. O’Malley“... is an oncogene in multiple cancers and is capable of potentiating numerous transcription factors in a wide...”
Publicado 2021
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22788por Meng-Kai Ge, Na Zhang, Li Xia, Cheng Zhang, Shuang-Shu Dong, Zhan-Ming Li, Yan Ji, Min-Hua Zheng, Jing Sun, Guo-Qiang Chen, Shao-Ming Shen“...Loss of nuclear PTEN is associated with aggressive cancers. Here the authors show that nuclear PTEN...”
Publicado 2020
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22789por Janet L. Markman, Rebecca A. Porritt, Daiko Wakita, Malcolm E. Lane, Daisy Martinon, Magali Noval Rivas, Michael Luu, Edwin M. Posadas, Timothy R. Crother, Moshe Arditi“...It is known that there are sex differences in the incidence and prognosis of certain cancers...”
Publicado 2020
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22790por Tatsuyuki Matsudaira, Kojiro Mukai, Taishin Noguchi, Junya Hasegawa, Tomohisa Hatta, Shun-ichiro Iemura, Tohru Natsume, Norio Miyamura, Hiroshi Nishina, Jun Nakayama, Kentaro Semba, Takuya Tomita, Shigeo Murata, Hiroyuki Arai, Tomohiko Taguchi“... the malignancy of various cancers, however its regulation is not fully understood. Here the authors show...”
Publicado 2017
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22791por Katharina Leonards, Marwa Almosailleakh, Samantha Tauchmann, Frederik Otzen Bagger, Cécile Thirant, Sabine Juge, Thomas Bock, Hélène Méreau, Matheus F. Bezerra, Alexandar Tzankov, Robert Ivanek, Régine Losson, Antoine H. F. M. Peters, Thomas Mercher, Juerg Schwaller“...Loss of function mutations of NSD1 occur in blood cancers. Here, the authors report that NSD1 loss...”
Publicado 2020
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22792por Xia Ding, Arnab Ray Chaudhuri, Elsa Callen, Yan Pang, Kajal Biswas, Kimberly D. Klarmann, Betty K. Martin, Sandra Burkett, Linda Cleveland, Stacey Stauffer, Teresa Sullivan, Aashish Dewan, Hanna Marks, Anthony T. Tubbs, Nancy Wong, Eugen Buehler, Keiko Akagi, Scott E. Martin, Jonathan R. Keller, André Nussenzweig, Shyam K. Sharan“... associated cancers. Here the authors show that olaparib can contribute to synthetic viability of cells...”
Publicado 2016
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22793por Laura Escudero, Anna Llort, Alexandra Arias, Ander Diaz-Navarro, Francisco Martínez-Ricarte, Carlota Rubio-Perez, Regina Mayor, Ginevra Caratù, Elena Martínez-Sáez, Élida Vázquez-Méndez, Iván Lesende-Rodríguez, Raquel Hladun, Luis Gros, Santiago Ramón y Cajal, Maria A. Poca, Xose S. Puente, Juan Sahuquillo, Soledad Gallego, Joan Seoane“...Non-invasive and precise methods are critical for monitoring paediatric brain cancers. Here...”
Publicado 2020
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22794por Lucia Cabal-Hierro, Peter van Galen, Miguel A. Prado, Kelly J. Higby, Katsuhiro Togami, Cody T. Mowery, Joao A. Paulo, Yingtian Xie, Paloma Cejas, Takashi Furusawa, Michael Bustin, Henry W. Long, David B. Sykes, Steven P. Gygi, Daniel Finley, Bradley E. Bernstein, Andrew A. Lane“... are frequently seen in cancers. Here, the authors show that the chromatin accessibility regulator HMGN1 - which...”
Publicado 2020
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22795por M. Udugama, L. Hii, A. Garvie, M. Cervini, B. Vinod, F.-L. Chan, P. P. Das, J. R. Mann, P. Collas, H. P. J. Voon, L. H. Wong“...% of cancers that have been associated with mutations in ATRX. Here the authors reveal a functional role...”
Publicado 2021
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22796por Jesse A. Rudd-Schmidt, Adrian W. Hodel, Tahereh Noori, Jamie A. Lopez, Hyun-Jung Cho, Sandra Verschoor, Annette Ciccone, Joseph A. Trapani, Bart W. Hoogenboom, Ilia Voskoboinik“...Cytotoxic T lymphocytes (CTLs) eliminate virus-infected and cancerous cells by secreting the pore...”
Publicado 2019
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22797por Zhikun Zhao, Lynn Goldin, Shiping Liu, Liang Wu, Weiyin Zhou, Hong Lou, Qichao Yu, Shirley X. Tsang, Miaomiao Jiang, Fuqiang Li, MaryLou McMaster, Yang Li, Xinxin Lin, Zhifeng Wang, Liqin Xu, Gerald Marti, Guibo Li, Kui Wu, Meredith Yeager, Huanming Yang, Xun Xu, Stephen J. Chanock, Bo Li, Yong Hou, Neil Caporaso, Michael Dean“...Studying the genetic progression of many cancers is difficult as longitudinal samples are rarely...”
Publicado 2016
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22798por Yangfan Qi, Jing Yu, Wei Han, Xiaojuan Fan, Haili Qian, Huanhuan Wei, Yi-hsuan S. Tsai, Jinyao Zhao, Wenjing Zhang, Quentin Liu, Songshu Meng, Yang Wang, Zefeng Wang“...The Hippo/Yap signalling pathway is found deregulated in several cancers. Here, the authors uncover...”
Publicado 2016
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22799por Liqing Tian, Ying Shao, Stephanie Nance, Jinjun Dang, Beisi Xu, Xiaotu Ma, Yongjin Li, Bensheng Ju, Li Dong, Scott Newman, Xin Zhou, Patrick Schreiner, Elizabeth Tseng, Ting Hon, Meredith Ashby, Chunliang Li, John Easton, Tanja A. Gruber, Jinghui Zhang“...The IGH@ proto-oncogene translocation is a known genomic driver in several blood cancers. Here...”
Publicado 2019
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22800por Weiwei Zhai, Tony Kiat-Hon Lim, Tong Zhang, Su-Ting Phang, Zenia Tiang, Peiyong Guan, Ming-Hwee Ng, Jia Qi Lim, Fei Yao, Zheng Li, Poh Yong Ng, Jie Yan, Brian K. Goh, Alexander Yaw-Fui Chung, Su-Pin Choo, Chiea Chuen Khor, Wendy Wei-Jia Soon, Ken Wing-Kin Sung, Roger Sik-Yin Foo, Pierce Kah-Hoe Chow“...Hepatocellular carcinoma has one of the poorest survival rates amongst cancers. Here, the authors...”
Publicado 2017
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