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  1. 7281
    TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins
    “...One of the major causes of cancer-related mortality is represented by metastatic lung cancer. Here...”
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  2. 7282
    Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction
    “...Predicting cancer risk requires large datasets and sophisticated models. Here the authors integrate...”
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  3. 7283
    Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap
    “...Microsatellite-stable (MSS) colorectal cancer (CRC) has shown poor response to checkpoint blockade...”
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  4. 7284
    Predictive biomarkers for 5-fluorouracil and oxaliplatin-based chemotherapy in gastric cancers via profiling of patient-derived xenografts
    “...Gastric cancer is commonly treated by chemotherapy using 5-fluorouracil derivatives and platinum...”
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  5. 7285
    TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation
    “... in many cancer types. Here, the authors show that TMBIM6 regulates AKT activation through mTORC2 assembly...”
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  6. 7286
    Disparities in access to health care system as determinant of survival for patients with pancreatic cancer in the State of São Paulo, Brazil
    “... cancer. We sought to describe the socio-economic characteristics, patterns of health care access...”
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  7. 7287
    Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation
    “... lowers its sensitivity to metabolic inhibitors leading to increased glycolysis and reduced cancer cell...”
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  8. 7288
    Non-invasive early detection of cancer four years before conventional diagnosis using a blood test
    “... detect cancer occurrence even in asymptomatic patients....”
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  9. 7289
    Differences among [18F]FDG PET-derived parameters in lung cancer produced by three software packages
    “... among three different software programs in lung cancer. A retrospective analysis was performed on a...”
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  10. 7290
    Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women
    por Babatunde Adedokun, Zhaohui Du, Guimin Gao, Thomas U. Ahearn, Kathryn L. Lunetta, Gary Zirpoli, Jonine Figueroa, Esther M. John, Leslie Bernstein, Wei Zheng, Jennifer J. Hu, Regina G. Ziegler, Sarah Nyante, Elisa V. Bandera, Sue A. Ingles, Michael F. Press, Sandra L. Deming-Halverson, Jorge L. Rodriguez-Gil, Song Yao, Temidayo O. Ogundiran, Oladosu Ojengbede, William Blot, Melissa A. Troester, Katherine L. Nathanson, Anselm Hennis, Barbara Nemesure, Stefan Ambs, Peter N. Fiorica, Lara E. Sucheston-Campbell, Jeannette T. Bensen, Lawrence H. Kushi, Gabriela Torres-Mejia, Donglei Hu, Laura Fejerman, Manjeet K. Bolla, Joe Dennis, Alison M. Dunning, Douglas F. Easton, Kyriaki Michailidou, Paul D. P. Pharoah, Qin Wang, Dale P. Sandler, Jack A. Taylor, Katie M. O’Brien, Cari M. Kitahara, Adeyinka G. Falusi, Chinedum Babalola, Joel Yarney, Baffour Awuah, Beatrice Addai-Wiafe, The GBHS Study Team, Stephen J. Chanock, Andrew F. Olshan, Christine B. Ambrosone, David V. Conti, Elad Ziv, Olufunmilayo I. Olopade, Montserrat Garcia-Closas, Julie R. Palmer, Christopher A. Haiman, Dezheng Huo
    Publicado 2021
    “...GWAS have enhanced our understanding for the genetic basis of breast cancer, but the majority...”
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  11. 7291
    RhoGAP domain-containing fusions and PPAPDC1A fusions are recurrent and prognostic in diffuse gastric cancer
    “...Diffuse Gastric Cancer (DGC) is increasingly being considered separate to intestinal type gastric...”
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  12. 7292
    Patients with genetically heterogeneous synchronous colorectal cancer carry rare damaging germline mutations in immune-related genes
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  13. 7293
    Development of diabetes mellitus following hormone therapy in prostate cancer patients is associated with early progression to castration resistance
    “...Abstract To identify risk factors for the prognosis of prostate cancer (PC), we retrospectively...”
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  14. 7294
    Publisher Correction: Phosphorylation of the proline-rich domain of WAVE3 drives its oncogenic activity in breast cancer
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  15. 7295
    Impact of endoscopic submucosal dissection and epithelial cell sheet engraftment on systemic cytokine dynamics in patients with oesophageal cancer
    “...Abstract The tumour microenvironment (TME) plays an important role in cancer development...”
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  16. 7296
    Predictive role of circulatory HMGB1 in postoperative acute exacerbation of interstitial lung disease in lung cancer patients
    “... in patients with lung cancer concomitant with ILD. We aimed to elucidate the predictive potential of high...”
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  17. 7297
    Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
    “...There is still no consensus on tumour type-specific cancer stem cell markers. Here, the authors...”
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  18. 7298
    Integrating ensemble systems biology feature selection and bimodal deep neural network for breast cancer prognosis prediction
    por Li-Hsin Cheng, Te-Cheng Hsu, Che Lin
    Publicado 2021
    “...Abstract Breast cancer is a heterogeneous disease. To guide proper treatment decisions for each...”
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  19. 7299
    Cancer-associated fibroblasts are associated with poor prognosis in solid type of lung adenocarcinoma in a machine learning analysis
    “...Abstract Cancer-associated fibroblasts (CAFs) participate in critical processes in the tumor...”
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  20. 7300
    Implication of FDG-PET/CT without synchronous colonic lesion in patients with stenotic left-sided colorectal cancer
    “...-FDG PET/CT) is useful for detecting synchronous colorectal cancer (CRC) in stenotic CRC, long-term...”
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