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  1. 17601
    The clinical significance of glutathione peroxidase 2 in glioblastoma multiforme
    por Guo Bangming, Liao Wenjuan, Wang Shusheng
    Publicado 2021
    “...Glioblastoma multiforme (GBM) is the leading cause of death among adult brain cancer patients...”
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  2. 17602
    Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line
    “... of diseases such as cancer....”
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  3. 17603
    Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness
    “...How cancer-associated fibroblasts become activated to support metastasis is not well understood...”
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  4. 17604
    In situ supramolecular polymerization-enhanced self-assembly of polymer vesicles for highly efficient photothermal therapy
    “...Photothermal therapy (PTT) has recently emerged as a promising approach for cancer therapy. Here...”
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  5. 17605
    Molecular mechanism of the MORC4 ATPase activation
    “..., inflammatory disorders and cancer. Here the authors describe the structure–function relationship of MORC4...”
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  6. 17606
    Redox regulation of EGFR steers migration of hypoxic mammary cells towards oxygen
    “...Aerotaxis, chemotaxis towards oxygen, occurs in bacteria and likely in cancer cells. Here...”
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  7. 17607
    Discovery of a small protein-encoding cis-regulatory overlapping gene of the tumor suppressor gene Scribble in humans
    por Yuhta Nomura, Naoshi Dohmae
    Publicado 2021
    “... the translation of downstream Scribble and may have important implications in cancer....”
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  8. 17608
    A stem cell population at the anorectal junction maintains homeostasis and participates in tissue regeneration
    “..., and contribute to cancer development. Here, the authors examine the mouse anorectal junction, identifying a...”
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  9. 17609
    Predicting treatment benefit in multiple myeloma through simulation of alternative treatment effects
    “...Selection of the right cancer treatment is still a challenge. Here, the authors introduce a...”
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  10. 17610
    SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival
    “...T-acute lymphoblastic leukemia is an aggressive cancer. Here the authors provide insights...”
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  11. 17611
    Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells
    “...Cancer cells can disrupt cell-to-cell junctions, thus allowing migration and metastasis. Here...”
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  12. 17612
    Rational combination of oncolytic vaccinia virus and PD-L1 blockade works synergistically to enhance therapeutic efficacy
    “...Anti-PD-L1 therapy often fails in cancers with minimal lymphocytic infiltrates and low PD-L1...”
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  13. 17613
    Deciphering the complex role of thrombospondin-1 in glioblastoma development
    “...Thrombospondin-1 (THSB1) is a component of the ECM with a role in regulating cancer development...”
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  14. 17614
    Reversible histone glycation is associated with disease-related changes in chromatin architecture
    “..., provide evidence that it affects chromatin, particularly in breast cancer, and identify DJ-1 as a...”
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  15. 17615
    Checkpoint blockade and nanosonosensitizer-augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice
    “...Immunotherapy for the treatment of cancer can be complicated by side effects and poor efficacy...”
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  16. 17616
    A FRET biosensor reveals spatiotemporal activation and functions of aurora kinase A in living cells
    “... associated with cancer progression. Here the authors develop a FRET biosensor which functionally replaces...”
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  17. 17617
    CSL controls telomere maintenance and genome stability in human dermal fibroblasts
    “...Conversion of dermal fibroblasts into Cancer Associated Fibroblasts (CAFs) can play an important...”
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  18. 17618
    Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation
    “... suppressor cells, and delay the onset of colitis-associated cancer....”
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  19. 17619
    Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging
    “...Tumour-associated macrophages (TAM) can be used as prognostic indicators in cancer. Here...”
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  20. 17620
    DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity
    “... the immunogenicity of cancer cells treated with high radiation doses by degrading cytosolic DNA and preventing...”
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