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  1. 17861
    Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells
    “... are unclear. Here, the authors report that FASN promotes anaplerotic shift of the Krebs cycle in cancer cells...”
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  2. 17862
    Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach
    “...How a precancerous form (dysplasia) becomes gastric cancer is unclear. Here, the authors assess...”
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  3. 17863
    Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase
    “... for hypercholesteremia and cancer drug development. Here the authors present the crystal structures of the human SQLE...”
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  4. 17864
    Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition
    “... and therapeutic resistance in cancer. Here, the authors show organoids derived from mesenchymal breast cancers...”
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  5. 17865
    ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery
    “... a proteome signature library of drug-treated cancer cell lines and develop a software tool...”
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  6. 17866
    Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly
    “... signaling output in prostate cancer cells....”
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  7. 17867
    circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1
    “...Circular RNAs are known to regulate cancer. Here, the authors show that the circular RNA circTP63...”
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  8. 17868
    Author Correction: Gene correction for SCID-X1 in long-term hematopoietic stem cells
    “.... acknowledges the support from the Cancer Prevention and Research Institute of Texas (RR140081 and RR170721...”
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  9. 17869
    Small genomic insertions form enhancers that misregulate oncogenes
    “...Sequencing initiatives have detected multiple types of mutations in cancer. Here the authors...”
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  10. 17870
    Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors
    “...“Although aberrant promoter DNA hypermethylation is a hallmark of cancer, it is not clear whether...”
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  11. 17871
    Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90
    “...Cachexia affects many cancer patients causing weight loss and increasing mortality. Here...”
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  12. 17872
    An open source automated tumor infiltrating lymphocyte algorithm for prognosis in melanoma
    “...Histology data exists for many cancer samples and the ability to automatically image this data may...”
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  13. 17873
    Modulation of telomere protection by the PI3K/AKT pathway
    “...Regulation of telomeres and the insulin/PI3K pathway both have roles in aging and cancer...”
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  14. 17874
    The GPR171 pathway suppresses T cell activation and limits antitumor immunity
    “... GPR171 functions as a co-inhibitor of T cell signalling and might serve as a target for cancer...”
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  15. 17875
    Plk1 overexpression induces chromosomal instability and suppresses tumor development
    “...PLK1 is a mitotic regulator overexpressed in cancer; however, whether this overexpression causally...”
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  16. 17876
    Stromal-driven and Amyloid β-dependent induction of neutrophil extracellular traps modulates tumor growth
    “.... Here the authors show that Amyloid β proteins from cancer-associated fibroblasts (CAF) induce...”
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  17. 17877
    Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1
    “...Human indoleamine 2,3-dioxygenase 1 (hIDO1) is an immunotherapeutic target for cancer therapy. Here...”
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  18. 17878
    H2S-activatable near-infrared afterglow luminescent probes for sensitive molecular imaging in vivo
    “... and demonstrate the measurement of hydrogen sulphide levels and the labelling of hepatic cancer specimens in vivo....”
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  19. 17879
    NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis
    “...The authors use an integrative clustering approach to identify two laryngeal cancer clusters...”
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  20. 17880
    CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG
    “...Embryonal rhabdomyosarcoma (ERMS) is a childhood cancer with impaired myogenic differentiation...”
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