Impact of dose-dense neoadjuvant chemotherapy on pathologic response and survival for HER2-positive breast cancer patients who receive trastuzumab

por Lize Wang, Yang Zhang, Yingjian He, Jinfeng Li, Tianfeng Wang, Yuntao Xie, Zhaoqing Fan, Tao Ouyang
Publicado 2021

Cancer-specific immune evasion and substantial heterogeneity within cancer types provide evidence for personalized immunotherapy

por Martin Thelen, Kerstin Wennhold, Jonas Lehmann, Maria Garcia-Marquez, Sebastian Klein, Elena Kochen, Philipp Lohneis, Axel Lechner, Svenja Wagener-Ryczek, Patrick Sven Plum, Oscar Velazquez Camacho, David Pfister, Fabian Dörr, Matthias Heldwein, Khosro Hekmat, Dirk Beutner, Jens Peter Klussmann, Fabinshy Thangarajah, Dominik Ratiu, Wolfram Malter, Sabine Merkelbach-Bruse, Christiane Josephine Bruns, Alexander Quaas, Michael von Bergwelt-Baildon, Hans A. Schlößer
Publicado 2021

Interim clinical trial analysis of intraoperative mass spectrometry for breast cancer surgery

por Sankha S. Basu, Sylwia A. Stopka, Walid M. Abdelmoula, Elizabeth C. Randall, Begoña Gimenez-Cassina Lopez, Michael S. Regan, David Calligaris, Fake F. Lu, Isaiah Norton, Melissa A. Mallory, Sandro Santagata, Deborah A. Dillon, Mehra Golshan, Nathalie Y. R. Agar
Publicado 2021

Circulating tumor cell number and endocrine therapy index in ER positive metastatic breast cancer patients

por Costanza Paoletti, Meredith M. Regan, Samuel M. Niman, Emily M. Dolce, Elizabeth P. Darga, Minetta C. Liu, P. Kelly Marcom, Lowell L. Hart, John W. Smith, Karen L. Tedesco, Eitan Amir, Ian E. Krop, Angela M. DeMichele, Pamela J. Goodwin, Margaret Block, Kimberly Aung, Martha E. Brown, Robert T. McCormack, Daniel F. Hayes
Publicado 2021

Overcoming resistance to BRAFV600E inhibition in melanoma by deciphering and targeting personalized protein network alterations

por S. Vasudevan, E. Flashner-Abramson, Heba Alkhatib, Sangita Roy Chowdhury, I. A. Adejumobi, D. Vilenski, S. Stefansky, A. M. Rubinstein, N. Kravchenko-Balasha
Publicado 2021

Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA

por Justin D. Finkle, Hala Boulos, Terri M. Driessen, Christine Lo, Richard A. Blidner, Ashraf Hafez, Aly A. Khan, Ariane Lozac’hmeur, Kelly E. McKinnon, Jason Perera, Wei Zhu, Afshin Dowlati, Kevin P. White, Robert Tell, Nike Beaubier
Publicado 2021

Comprehensive molecular profiling of pulmonary pleomorphic carcinoma

por Masaaki Nagano, Shinji Kohsaka, Takuo Hayashi, Toshihide Ueno, Shinya Kojima, Aya Shinozaki-Ushiku, Shigeki Morita, Masumi Tsuda, Shinya Tanaka, Toshiya Shinohara, Yuko Omori, Fumiko Sugaya, Hiroaki Kato, Yoshiaki Narita, Jun Nakajima, Kenji Suzuki, Kazuya Takamochi, Hiroyuki Mano
Publicado 2021

Recurrence biomarkers of triple negative breast cancer treated with neoadjuvant chemotherapy and anti-EGFR antibodies

por Nina Radosevic-Robin, Pier Selenica, Yingjie Zhu, Helen H. Won, Michael F. Berger, Lorenzo Ferrando, Emiliano Cocco, Maud Privat, Flora Ponelle-Chachuat, Catherine Abrial, Jean-Marc Nabholtz, Frederique Penault-Llorca, Jorge S. Reis-Filho, Maurizio Scaltriti
Publicado 2021

Author Correction: Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis

por Vincenza Conteduca, Sheng-Yu Ku, Luisa Fernandez, Angel Dago-Rodriquez, Jerry Lee, Adam Jendrisak, Megan Slade, Cole Gilbertson, Jyothi Manohar, Michael Sigouros, Yipeng Wang, Ryan Dittamore, Rick Wenstrup, Juan Miguel Mosquera, Joseph D. Schonhoft, Himisha Beltran
Publicado 2021

The clinical and molecular significance associated with STING signaling in breast cancer

por Eileen E. Parkes, Matthew P. Humphries, Elaine Gilmore, Fatima A. Sidi, Victoria Bingham, Su M. Phyu, Stephanie Craig, Catherine Graham, Joseph Miller, Daryl Griffin, Manuel Salto-Tellez, Stephen F. Madden, Richard D. Kennedy, Samuel F. Bakhoum, Stephen McQuaid, Niamh E. Buckley
Publicado 2021

Criteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology

por Frank P. Lin, Subotheni Thavaneswaran, John P. Grady, Mandy Ballinger, Maya Kansara, Samantha R. Oakes, Jayesh Desai, Chee Khoon Lee, John Simes, David M. Thomas
Publicado 2021

Composite risk and benefit from adjuvant dose-dense chemotherapy in hormone receptor-positive breast cancer

por Fabio Puglisi, Lorenzo Gerratana, Matteo Lambertini, Marcello Ceppi, Luca Boni, Filippo Montemurro, Stefania Russo, Claudia Bighin, Michelino De Laurentiis, Mario Giuliano, Giancarlo Bisagni, Antonio Durando, Anna Turletti, Ornella Garrone, Andrea Ardizzoni, Teresa Gamucci, Giuseppe Colantuoni, Adriano Gravina, Sabino De Placido, Francesco Cognetti, Lucia Del Mastro
Publicado 2021

Identification of gastric cancer subtypes based on pathway clustering

por Lin Li, Xiaosheng Wang
Publicado 2021

SOX4 and SMARCA4 cooperatively regulate PI3k signaling through transcriptional activation of TGFBR2

por Gaurav A. Mehta, Steven P. Angus, Christen A. Khella, Kevin Tong, Pooja Khanna, Shelley A. H. Dixon, Michael P. Verzi, Gary L. Johnson, Michael L. Gatza
Publicado 2021

Interaction between CD36 and FABP4 modulates adipocyte-induced fatty acid import and metabolism in breast cancer

por Jones Gyamfi, Joo Hye Yeo, Doru Kwon, Byung Soh Min, Yoon Jin Cha, Ja Seung Koo, Joon Jeong, Jinu Lee, Junjeong Choi
Publicado 2021

Systematic tissue collection during clinical breast biopsy is feasible, safe and enables high-content translational analyses

por Siang-Boon Koh, Brian N. Dontchos, Veerle Bossuyt, Christine Edmonds, Simona Cristea, Nsan Melkonjan, Lindsey Mortensen, Annie Ma, Kassidy Beyerlin, Elyssa Denault, Elizabeth Niehoff, Taghreed Hirz, David B. Sykes, Franziska Michor, Michelle Specht, Constance Lehman, Leif W. Ellisen, Laura M. Spring
Publicado 2021

Effect of metformin versus placebo on metabolic factors in the MA.32 randomized breast cancer trial

por Pamela J. Goodwin, Ryan J. O. Dowling, Marguerite Ennis, Bingshu E. Chen, Wendy R. Parulekar, Lois E. Shepherd, Margot J. Burnell, Rachel Vander Meer, Andrea Molckovsky, Anagha Gurjal, Karen A. Gelmon, Jennifer A. Ligibel, Dawn L. Hershman, Ingrid A. Mayer, Timothy J. Whelan, Timothy J. Hobday, Priya Rastogi, Manuela Rabaglio-Poretti, Julie Lemieux, Alastair M. Thompson, Daniel W. Rea, Vuk Stambolic
Publicado 2021

Investigation of monogenic causes of familial breast cancer: data from the BEACCON case-control study

por Na Li, Belle W. X. Lim, Ella R. Thompson, Simone McInerny, Magnus Zethoven, Dane Cheasley, Simone M. Rowley, Michelle W. Wong-Brown, Lisa Devereux, Kylie L. Gorringe, Erica K. Sloan, Alison Trainer, Rodney J. Scott, Paul A. James, Ian G. Campbell
Publicado 2021

Clinical application of a lung cancer organoid (tumoroid) culture system

por Etsuko Yokota, Miki Iwai, Takuro Yukawa, Masakazu Yoshida, Yoshio Naomoto, Minoru Haisa, Yasumasa Monobe, Nagio Takigawa, Minzhe Guo, Yutaka Maeda, Takuya Fukazawa, Tomoki Yamatsuji
Publicado 2021

Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

por G. Emerens Wensink, Sjoerd G. Elias, Jasper Mullenders, Miriam Koopman, Sylvia F. Boj, Onno W. Kranenburg, Jeanine M. L. Roodhart
Publicado 2021