Circulating cell-free DNA-based methylation patterns for breast cancer diagnosis

por Xianyu Zhang, Dezhi Zhao, Yanling Yin, Ting Yang, Zilong You, Dalin Li, Yanbo Chen, Yongdong Jiang, Shouping Xu, Jingshu Geng, Yashuang Zhao, Jun Wang, Hui Li, Jinsheng Tao, Shan Lei, Zeyu Jiang, Zhiwei Chen, Shihui Yu, Jian-Bing Fan, Da Pang
Publicado 2021

Anti-tumor effects of an ID antagonist with no observed acquired resistance

por Paulina M. Wojnarowicz, Marta Garcia Escolano, Yun-Han Huang, Bina Desai, Yvette Chin, Riddhi Shah, Sijia Xu, Saurabh Yadav, Sergey Yaklichkin, Ouathek Ouerfelli, Rajesh Kumar Soni, John Philip, David C. Montrose, John H. Healey, Vinagolu K. Rajasekhar, William A. Garland, Jeremy Ratiu, Yuan Zhuang, Larry Norton, Neal Rosen, Ronald C. Hendrickson, Xi Kathy Zhou, Antonio Iavarone, Joan Massague, Andrew J. Dannenberg, Anna Lasorella, Robert Benezra
Publicado 2021

Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection

por Alexa C. Glencer, Jasmine M. Wong, Nola M. Hylton, Gregor Krings, Emma McCune, Harriet T. Rothschild, Tristan A. Loveday, Michael D. Alvarado, Laura J. Esserman, Michael J. Campbell
Publicado 2021

Breast adipocyte size associates with ipsilateral invasive breast cancer risk after ductal carcinoma in situ

por Mathilde M. M. Almekinders, Michael Schaapveld, Bram Thijssen, Lindy L. Visser, Tycho Bismeijer, Joyce Sanders, Edoardo Isnaldi, Ingrid Hofland, Marjolijn Mertz, Lodewyk F. A. Wessels, Annegien Broeks, Erik Hooijberg, Wilbert Zwart, Esther H. Lips, Grand Challenge PRECISION Consortium, Christine Desmedt, Jelle Wesseling
Publicado 2021

Circulating stromal cells in resectable pancreatic cancer correlates to pathological stage and predicts for poor clinical outcomes

por Kirby P. Gardner, Mohammed Aldakkak, Cha-Mei Tang, Susan Tsai, Daniel L. Adams
Publicado 2021

PONDx: real-life utilization and decision impact of the 21-gene assay on clinical practice in Italy

por Francesco Cognetti, Riccardo Masetti, Alessandra Fabi, Giulia Bianchi, Donatella Santini, Alessia Rognone, Giovanna Catania, Domenico Angelucci, Giuseppe Naso, Mario Giuliano, Lucia Vassalli, Patrizia Vici, Giovanni Scognamiglio, Daniele Generali, Alberto Zambelli, Marco Colleoni, Corrado Tinterri, Francesco Scanzi, Leonardo Vigna, Paola Scavina, Teresa Gamucci, Emilia Marrazzo, Angelo Fedele Scinto, Rossana Berardi, Maria Agnese Fabbri, Graziella Pinotti, Daniela Franco, Daniela Andreina Terribile, Giuseppe Tonini, Daniela Cianniello, Sandro Barni
Publicado 2021

A genomic mutation signature predicts the clinical outcomes of immunotherapy and characterizes immunophenotypes in gastrointestinal cancer

por Xi Jiao, Xin Wei, Shuang Li, Chang Liu, Huan Chen, Jifang Gong, Jian Li, Xiaotian Zhang, Xicheng Wang, Zhi Peng, Changsong Qi, Zhenghang Wang, Yujiao Wang, Yanni Wang, Na Zhuo, Henghui Zhang, Zhihao Lu, Lin Shen
Publicado 2021

The CINSARC signature predicts the clinical outcome in patients with Luminal B breast cancer

por Anthony Goncalves, Pascal Finetti, Daniel Birnbaum, François Bertucci
Publicado 2021

Structural variant detection in cancer genomes: computational challenges and perspectives for precision oncology

por Ianthe A. E. M. van Belzen, Alexander Schönhuth, Patrick Kemmeren, Jayne Y. Hehir-Kwa
Publicado 2021

Splicing profile by capture RNA-seq identifies pathogenic germline variants in tumor suppressor genes

por Tyler Landrith, Bing Li, Ashley A. Cass, Blair R. Conner, Holly LaDuca, Danielle B. McKenna, Kara N. Maxwell, Susan Domchek, Nichole A. Morman, Christopher Heinlen, Deborah Wham, Cathryn Koptiuch, Jennie Vagher, Ragene Rivera, Ann Bunnell, Gayle Patel, Jennifer L. Geurts, Morgan M. Depas, Shraddha Gaonkar, Sara Pirzadeh-Miller, Rebekah Krukenberg, Meredith Seidel, Robert Pilarski, Meagan Farmer, Khateriaa Pyrtel, Kara Milliron, John Lee, Elizabeth Hoodfar, Deepika Nathan, Amanda C. Ganzak, Sitao Wu, Huy Vuong, Dong Xu, Aarani Arulmoli, Melissa Parra, Lily Hoang, Bhuvan Molparia, Michele Fennessy, Susanne Fox, Sinead Charpentier, Julia Burdette, Tina Pesaran, Jessica Profato, Brandon Smith, Ginger Haynes, Emily Dalton, Joy Rae-Radecki Crandall, Ruth Baxter, Hsiao-Mei Lu, Brigette Tippin-Davis, Aaron Elliott, Elizabeth Chao, Rachid Karam
Publicado 2020

Resistance is futile: overcoming resistance to targeted therapies in lung adenocarcinoma

por Dana S. Neel, Trever G. Bivona
Publicado 2017

Endothelial cell malignancies: new insights from the laboratory and clinic

por Michael J. Wagner, Vinod Ravi, David G. Menter, Anil K. Sood
Publicado 2017

Precision cell-free DNA extraction for liquid biopsy by integrated microfluidics

por Hoyoon Lee, Chanhee Park, Wonhwi Na, Kyong Hwa Park, Sehyun Shin
Publicado 2020

ALK G1269A mutation as a potential mechanism of acquired resistance to crizotinib in an ALK-rearranged inflammatory myofibroblastic tumor

por Sebastian Y. F. Michels, Andreas H. Scheel, Thomas Wündisch, Johannes M. Heuckmann, Roopika Menon, Michael Puesken, Carsten Kobe, Helen Pasternack, Carina Heydt, Matthias Scheffler, Rieke Fischer, Anne M. Schultheis, Sabine Merkelbach-Bruse, Lukas Heukamp, Reinhard Büttner, Jürgen Wolf
Publicado 2017

Rare deleterious germline variants and risk of lung cancer

por Yanhong Liu, Jun Xia, James McKay, Spiridon Tsavachidis, Xiangjun Xiao, Margaret R. Spitz, Chao Cheng, Jinyoung Byun, Wei Hong, Yafang Li, Dakai Zhu, Zhuoyi Song, Susan M. Rosenberg, Michael E. Scheurer, Farrah Kheradmand, Claudio W. Pikielny, Christine M. Lusk, Ann G. Schwartz, Ignacio I. Wistuba, Michael H. Cho, Edwin K. Silverman, Joan Bailey-Wilson, Susan M. Pinney, Marshall Anderson, Elena Kupert, Colette Gaba, Diptasri Mandal, Ming You, Mariza de Andrade, Ping Yang, Triantafillos Liloglou, Michael P. A. Davies, Jolanta Lissowska, Beata Swiatkowska, David Zaridze, Anush Mukeria, Vladimir Janout, Ivana Holcatova, Dana Mates, Jelena Stojsic, Ghislaine Scelo, Paul Brennan, Geoffrey Liu, John K. Field, Rayjean J. Hung, David C. Christiani, Christopher I. Amos
Publicado 2021

Dual- versus single-agent HER2 inhibition and incidence of intracranial metastatic disease: a systematic review and meta-analysis

por Anders Wilder Erickson, Steven Habbous, Christianne Hoey, Katarzyna J. Jerzak, Sunit Das
Publicado 2021

Synergistic activation of mutant TERT promoter by Sp1 and GABPA in BRAFV600E-driven human cancers

por Yongxing Wu, Liang Shi, Yuelei Zhao, Pu Chen, Rongrong Cui, Meiju Ji, Nongyue He, Maode Wang, Gang Li, Peng Hou
Publicado 2021

Benefits of local consolidative treatment in oligometastases of solid cancers: a stepwise-hierarchical pooled analysis and systematic review

por Chai Hong Rim, In-Soo Shin, Sunmin Park, Hye Yoon Lee
Publicado 2021

Precision oncology- the future of personalized cancer medicine?

por Ann M. Bode, Zigang Dong
Publicado 2017

Targeting ornithine decarboxylase (ODC) inhibits esophageal squamous cell carcinoma progression

por Wei He, Eunmiri Roh, Ke Yao, Kangdong Liu, Xing Meng, Fangfang Liu, Penglei Wang, Ann M. Bode, Zigang Dong
Publicado 2017