Proteomics-derived basal biomarker DNA-PKcs is associated with intrinsic subtype and long-term clinical outcomes in breast cancer

por Karama Asleh, Nazia Riaz, Angela S. Cheng, Dongxia Gao, Samuel C. Y. Leung, Meenakshi Anurag, Torsten O. Nielsen
Publicado 2021

Clinical consequences of BRCA2 hypomorphism

por Laia Castells-Roca, Sara Gutiérrez-Enríquez, Sandra Bonache, Massimo Bogliolo, Estela Carrasco, Miriam Aza-Carmona, Gemma Montalban, Núria Muñoz-Subirana, Roser Pujol, Cristina Cruz, Alba Llop-Guevara, María J. Ramírez, Cristina Saura, Adriana Lasa, Violeta Serra, Orland Diez, Judith Balmaña, Jordi Surrallés
Publicado 2021

Models that combine transcriptomic with spatial protein information exceed the predictive value for either single modality

por Ioannis A. Vathiotis, Zhi Yang, Jason Reeves, Maria Toki, Thazin Nwe Aung, Pok Fai Wong, Harriet Kluger, Konstantinos N. Syrigos, Sarah Warren, David L. Rimm
Publicado 2021

Pentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma

por Michelle R. Goulart, Jennifer Watt, Imran Siddiqui, Rita T. Lawlor, Ahmet Imrali, Christine Hughes, Amina Saad, Joanne ChinAleong, Chris Hurt, Catrin Cox, Roberto Salvia, Alberto Mantovani, Tatjana Crnogorac-Jurcevic, Somnath Mukherjee, Aldo Scarpa, Paola Allavena, Hemant M. Kocher
Publicado 2021

Spatial distribution of B cells and lymphocyte clusters as a predictor of triple-negative breast cancer outcome

por Juliana C. Wortman, Ting-Fang He, Shawn Solomon, Robert Z. Zhang, Anthony Rosario, Roger Wang, Travis Y. Tu, Daniel Schmolze, Yuan Yuan, Susan E. Yost, Xuefei Li, Herbert Levine, Gurinder Atwal, Peter P. Lee, Clare C. Yu
Publicado 2021

Allostatic load: a framework to understand breast cancer outcomes in Black women

por Samilia Obeng-Gyasi, Willi Tarver, Ruth C. Carlos, Barbara L. Andersen
Publicado 2021

Impressive response to dabrafenib, trametinib, and osimertinib in a metastatic EGFR-mutant/BRAF V600E lung adenocarcinoma patient

por Maurício Fernando Silva Almeida Ribeiro, Franciele Hinterholz Knebel, Fabiana Bettoni, Rodrigo Saddi, Karina Perez Sacardo, Felipe Sales Nogueira Amorim Canedo, João Victor Machado Alessi, Andrea Kazumi Shimada, José Flávio Gomes Marin, Anamaria Aranha Camargo, Artur Katz
Publicado 2021

Clinical implications of systemic and local immune responses in human angiosarcoma

por Jason Yongsheng Chan, Grace Fangmin Tan, Joe Yeong, Chee Wee Ong, Dave Yong Xiang Ng, Elizabeth Lee, Joanna Koh, Cedric Chuan-Young Ng, Jing Yi Lee, Wei Liu, Ru Xin Wong, Chin-Ann Johnny Ong, Mohamad Farid, Bin Tean Teh, Khee Chee Soo
Publicado 2021

Novel evolutionary dynamics of small populations in breast cancer adjuvant and neoadjuvant therapy

por Yael Artzy-Randrup, Tamir Epstein, Joel S. Brown, Ricardo L. B. Costa, Brian J. Czerniecki, Robert A. Gatenby
Publicado 2021

Ivermectin converts cold tumors hot and synergizes with immune checkpoint blockade for treatment of breast cancer

por Dobrin Draganov, Zhen Han, Aamir Rana, Nitasha Bennett, Darrell J. Irvine, Peter P. Lee
Publicado 2021

Circulating tumor cells: quintessential precision oncology presenting challenges for biology

por Rebecca J. Morris
Publicado 2017

Inhibiting breast cancer by targeting the thromboxane A2 pathway

por Haitao Li, Mee-Hyun Lee, Kangdong Liu, Ting Wang, Mengqiu Song, Yaping Han, Ke Yao, Hua Xie, Feng Zhu, Michael Grossmann, Margot P. Cleary, Wei Chen, Ann M. Bode, Zigang Dong
Publicado 2017

Network-based machine learning and graph theory algorithms for precision oncology

por Wei Zhang, Jeremy Chien, Jeongsik Yong, Rui Kuang
Publicado 2017

A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial

por Istvan Petak, Maud Kamal, Anna Dirner, Ivan Bieche, Robert Doczi, Odette Mariani, Peter Filotas, Anne Salomon, Barbara Vodicska, Vincent Servois, Edit Varkondi, David Gentien, Dora Tihanyi, Patricia Tresca, Dora Lakatos, Nicolas Servant, Julia Deri, Pauline du Rusquec, Csilla Hegedus, Diana Bello Roufai, Richard Schwab, Celia Dupain, Istvan T. Valyi-Nagy, Christophe Le Tourneau
Publicado 2021

The pan-cancer landscape of crosstalk between epithelial-mesenchymal transition and immune evasion relevant to prognosis and immunotherapy response

por Guangyu Wang, Dandan Xu, Zicheng Zhang, Xinhui Li, Jiaqi Shi, Jie Sun, Huan-Zhong Liu, Xiaobo Li, Meng Zhou, Tongsen Zheng
Publicado 2021

Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor

por Christopher Alvarez-Breckenridge, Julie J. Miller, Naema Nayyar, Corey M. Gill, Andrew Kaneb, Megan D’Andrea, Long P. Le, Jesse Lee, Ju Cheng, Zongli Zheng, William E. Butler, Pratik Multani, Edna Chow Maneval, Sun Ha Paek, Brian D. Toyota, Dora Dias-Santagata, Sandro Santagata, Javier Romero, Alice T. Shaw, Anna F. Farago, Stephen Yip, Daniel P. Cahill, Tracy T. Batchelor, A. John Iafrate, Priscilla K. Brastianos
Publicado 2017

Birinapant sensitizes platinum-resistant carcinomas with high levels of cIAP to carboplatin therapy

por V. La, R. Fujikawa, D. M. Janzen, M. Nunez, L. Bainvoll, L. Hwang, K. Faull, G. Lawson, S. Memarzadeh
Publicado 2017

Chromosomal breaks at FRA18C: association with reduced DOK6 expression, altered oncogenic signaling and increased gastric cancer survival

por Siew Hong Leong, Kyaw Myo Lwin, Sze Sing Lee, Wai Har Ng, Kia Min Ng, Soo Yong Tan, Bee Ling Ng, Nigel P. Carter, Carol Tang, Oi Lian Kon
Publicado 2017

Revisiting the IGF-1R as a breast cancer target

por Roudy Chiminch Ekyalongo, Douglas Yee
Publicado 2017

Prediction of quality of life in early breast cancer upon completion of adjuvant chemotherapy

por Alberto Carmona-Bayonas, Caterina Calderón, Raquel Hernández, Ana Fernández Montes, Beatriz Castelo, Laura Ciria-Suarez, Mónica Antoñanzas, Jacobo Rogado, Vilma Pacheco-Barcia, Elena Asensio Martínez, Alejandra Ivars, Francisco Ayala de la Peña, Paula Jimenez-Fonseca
Publicado 2021