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321por Kristen E. Clements, Emily M. Schleicher, Tanay Thakar, Anastasia Hale, Ashna Dhoonmoon, Nathanial J. Tolman, Anchal Sharma, Xinwen Liang, Yuka Imamura Kawasawa, Claudia M. Nicolae, Hong-Gang Wang, Subhajyoti De, George-Lucian Moldovan“... the authors by genome-wide CRISPR knockout and activation screens reveal novel pathways of PARPi resistance...”
Publicado 2020
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322
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323por Mindong Liang, Zilong Li, Weishan Wang, Jiakun Liu, Leshi Liu, Guoliang Zhu, Loganathan Karthik, Man Wang, Ke-Feng Wang, Zhong Wang, Jing Yu, Yuting Shuai, Jiaming Yu, Lu Zhang, Zhiheng Yang, Chuan Li, Qian Zhang, Tong Shi, Liming Zhou, Feng Xie, Huanqin Dai, Xueting Liu, Jingyu Zhang, Guang Liu, Ying Zhuo, Buchang Zhang, Chenli Liu, Shanshan Li, Xuekui Xia, Yaojun Tong, Yanwen Liu, Gil Alterovitz, Gao-Yi Tan, Li-Xin ZhangEnlace del recurso
Publicado 2019
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324por Mikihiro Shibata, Hiroshi Nishimasu, Noriyuki Kodera, Seiichi Hirano, Toshio Ando, Takayuki Uchihashi, Osamu Nureki“...CRISPR RNA-guided endonuclease Cas9 recognizes and cleaves the double-stranded DNA complementary...”
Publicado 2017
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325“... CRISPR/Cas9 to disrupt dopamine beta hydroxylase in LC neurons and see this reduces LC-evoked sleep...”
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326“... to gene expression remains poorly understood. Here the authors apply in vivo CRISPR/Cas9 genome...”
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327por Jurre A. Steens, Yifan Zhu, David W. Taylor, Jack P. K. Bravo, Stijn H. P. Prinsen, Cor D. Schoen, Bart J. F. Keijser, Michel Ossendrijver, L. Marije Hofstra, Stan J. J. Brouns, Akeo Shinkai, John van der Oost, Raymond H. J. Staals“...Type III CRISPR-Cas systems recognize and cleave target RNAs and produce signalling molecules. Here...”
Publicado 2021
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328por Raymond H. J. Staals, Simon A. Jackson, Ambarish Biswas, Stan J. J. Brouns, Chris M. Brown, Peter C. Fineran“...Prokaryotic CRISPR-Cas systems provide adaptive immunity against foreign nucleic acids by acquiring...”
Publicado 2016
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329por Yan-Mei Zheng, Fu-Long Lin, Hao Gao, Gen Zou, Jiang-Wei Zhang, Gao-Qian Wang, Guo-Dong Chen, Zhi-Hua Zhou, Xin-Sheng Yao, Dan Hu“... the low yields of bioactive metabolites and expanding chemical diversity. The CRISPR-Cas9-based system has...”
Publicado 2017
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330“...Abstract CRISPR/Cas9 gene editing is effective in manipulating genetic loci in mammalian cell...”
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331
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332por Yunkai Zhu, Fei Feng, Gaowei Hu, Yuyan Wang, Yin Yu, Yuanfei Zhu, Wei Xu, Xia Cai, Zhiping Sun, Wendong Han, Rong Ye, Di Qu, Qiang Ding, Xinxin Huang, Hongjun Chen, Wei Xu, Youhua Xie, Qiliang Cai, Zhenghong Yuan, Rong Zhang“... and identify host factors affecting entry of SARS-CoV-2 in a genome-wide CRISPR screen....”
Publicado 2021
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333“... of related tools such as CRISPR-Cas9 depends on the efficiency of delivery to the targeted cells. Numerous...”
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334
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335“...Off-target effects often confound the interpretation of CRISPR screens. Here, the authors introduce...”
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336por Sanju Sinha, Karina Barbosa, Kuoyuan Cheng, Mark D. M. Leiserson, Prashant Jain, Anagha Deshpande, David M. Wilson, Bríd M. Ryan, Ji Luo, Ze’ev A. Ronai, Joo Sang Lee, Aniruddha J. Deshpande, Eytan Ruppin“...CRISPR-Cas9 gene editing can induce a p53 mediated damage response. Here the authors investigate...”
Publicado 2021
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337por Kathleen A. Joo, Michael G. Muszynski, Michael B. Kantar, Ming-Li Wang, Xiaoling He, Angel R. Del Valle Echevarria, Angel R. Del Valle EchevarriaMaterias: “...CRISPR-cas...”
Publicado 2021
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338por Rui Wei, Jiayin Yang, Chi-Wa Cheng, Wai-In Ho, Na Li, Yang Hu, Xueyu Hong, Jian Fu, Bo Yang, Yuqing Liu, Lixiang Jiang, Wing-Hon Lai, Ka-Wing Au, Wai-Ling Tsang, Yiu-Lam Tse, Kwong-Man Ng, Miguel A. Esteban, Hung-Fat TseMaterias: “...Clustered regularly interspaced palindromic repeats (CRISPR)/Cas9...”
Publicado 2022
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339“...CRISPR arrays and associated cas genes are widespread in bacteria and archaea and confer acquired...”
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340por Lia Carolina Soares Medeiros, Lilith South, Duo Peng, Juan M. Bustamante, Wei Wang, Molly Bunkofske, Natasha Perumal, Fernando Sanchez-Valdez, Rick L. TarletonMaterias: “...CRISPR...”
Publicado 2017
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