Mostrando 661 - 680 Resultados de 1,137 Para Buscar '"CRISPR"', tiempo de consulta: 0.05s Limitar resultados
  1. 661
    Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion
    “... interspaced short palindromic repeat (CRISPR) and CRISPR-associated gene 9 (CRISPR-cas9) gene targeting. When...”
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  2. 662
    A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection
    “... in murine and human cells. Employing a genome-wide CRISPR-Cas9 knockout screen to find host factors required...”
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  3. 663
    Efficient Generation of diRNAs Requires Components in the Posttranscriptional Gene Silencing Pathway
    “..., important questions remain regarding the biogenesis and function of diRNAs. Here, we used CRISPR/Cas9...”
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  4. 664
    Integrated cross-study datasets of genetic dependencies in cancer
    “...The integration of independent pan-cancer CRISPR-Cas9 datasets allows better representation...”
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  5. 665
    A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis
    “... luciferase (Gluc) enzyme, generated by the Clustered regularly interspaced short palindromic repeats (CRISPR...”
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  6. 666
    SgRNA Expression of CRIPSR-Cas9 System Based on MiRNA Polycistrons as a Versatile Tool to Manipulate Multiple and Tissue-Specific Genome Editing
    “...Abstract CRISPR/Cas9-mediated genome editing is a next-generation strategy for genetic...”
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  7. 667
    Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters
    “..., CRISPR-Cas9 and CRISPR-cBEST-mediated knockouts. Two out of the three native plasmids were cured using...”
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  8. 668
    Independent Microevolution Mediated by Mobile Genetic Elements of Individual <named-content content-type="genus-species">Clostridium difficile</named-content> Isolates from Clade 4 Revealed by Whole-Genome Sequencing
    “... and CRISPR arrays were identified in C. difficile isolates of clade 4. Approximately 20% of spacers were...”
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  9. 669
    SAMHD1 Regulates Human Papillomavirus 16-Induced Cell Proliferation and Viral Replication during Differentiation of Keratinocytes
    “...) is transcriptionally regulated by HPV16 in N/Tert-1. CRISPR/Cas9 removal of SAMHD1 from N/Tert-1 and N/Tert-1+HPV16...”
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  10. 670
    Prime Editing for Inherited Retinal Diseases
    “... palindromic repeats (CRISPR)-based technology to correct a specific genetic mutation within the endogenous...”
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  11. 671
    Tissue-specific activation of gene expression by the Synergistic Activation Mediator (SAM) CRISPRa system in mice
    “...CRISPR-Cas9 is a gene editing tool that can be used to modulate gene expression. Here, the authors...”
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  12. 672
    Rapid generation of a transgene-free powdery mildew resistant tomato by genome deletion
    “... variety resistant to the powdery mildew fungal pathogen using the CRISPR/Cas9 technology. We used whole...”
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  13. 673
    Cell Cycle Regulation by Alternative Polyadenylation of CCND1
    “..., we edited the weak poly(A) signal (PAS) of the proximal APA site to a canonical PAS using the CRISPR...”
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  14. 674
    DNA binding properties of the small cascade subunit Csa5.
    “...CRISPR-Cas systems provide immunity against viral attacks in archaeal and bacterial cells. Type I...”
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  15. 675
    High-risk clones of extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolated from the University Hospital Establishment of Oran, Algeria (2011-2012).
    “... Regularly Interspaced Short Palindromic Repeats-associated (CRISPR-Cas) system of extended-spectrum β...”
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  16. 676
    Detection of gene cis-regulatory element perturbations in single-cell transcriptomes.
    “...We introduce poly-adenine CRISPR gRNA-based single-cell RNA-sequencing (pAC-Seq), a method...”
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  17. 677
    Humanized GPRC6A KGKY is a gain-of-function polymorphism in mice
    “... genomic humanization of mice by using CRISPR/Cas9 (clustered regularly interspaced short palindromic...”
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  18. 678
    Runx1 shapes the chromatin landscape via a cascade of direct and indirect targets.
    “... show that CRISPR-mediated deletion of Runx1 in mouse metanephric mesenchyme-derived mK4 cells results...”
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  19. 679
    Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency
    “... Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system in conjunction with piggyBac technology...”
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  20. 680
    Evaluation of ATM heterozygous mutations underlying individual differences in radiosensitivity using genome editing in human cultured cells
    “... variation on radiosensitivity, we here used the CRISPR-ObLiGaRe (Obligate Ligation-Gated Recombination...”
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