Mostrando 961 - 980 Resultados de 1,137 Para Buscar '"CRISPR"', tiempo de consulta: 0.06s Limitar resultados
  1. 961
    Mitotic Centromere-Associated Kinesin (MCAK/KIF2C) Regulates Cell Migration and Invasion by Modulating Microtubule Dynamics and Focal Adhesion Turnover
    “... mechanisms were not completely clarified. To address these issues, we generated CRISPR/dCas9 HeLa and retinal...”
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  2. 962
    MiR 208a Regulates Mitochondrial Biogenesis in Metabolically Challenged Cardiomyocytes
    “..., and Sortin nexin 10 are rescued by the CRISPR deletion of miR 208a in human SV40 cardiomyocytes exposed...”
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  3. 963
    Trib1 deficiency causes brown adipose respiratory chain depletion and mitochondrial disorder
    “... regularly interspaced short palindromic repeats (CRISPR)/Cas9 technology. The metabolic function of the BAT...”
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  4. 964
    Facilitating Antiviral Drug Discovery Using Genetic and Evolutionary Knowledge
    “... interspersed short palindromic repeats (CRISPR) screening, etc.) for human diseases, providing valuable genetic...”
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  5. 965
    Virulence Comparison of <i>Salmonella enterica</i> Subsp. <i>enterica</i> Isolates from Chicken and Whole Genome Analysis of the High Virulent Strain <i>S</i>. Enteritidis 211
    “..., and prophage regions. The MGEs and CRISPR-Cas system might function synergistically for gene transfer...”
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  6. 966
    Molecular Mechanisms of Cereblon-Interacting Small Molecules in Multiple Myeloma Therapy
    “... functions, including endogenous substrates and chaperone activity. CRISPR Cas9-based genome-wide screening...”
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  7. 967
    Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells
    “... about the metabolic dependencies of other critical signals such as interferon gamma (IFNγ). Using CRISPR...”
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  8. 968
    Host specific diversity in Lactobacillus johnsonii as evidenced by a major chromosomal inversion and phage resistance mechanisms.
    “... was identified, as were novel Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) elements...”
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  9. 969
    Sequencing and validation of the genome of a Campylobacter concisus reveals intra-species diversity.
    “... associated gene clusters. These included one associated with the CRISPR family and another which encoded...”
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  10. 970
    Phage encoded H-NS: a potential achilles heel in the bacterial defence system.
    “.... These genes include CRISPR associated proteins and a Type III restriction-modification system, which are key...”
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  11. 971
    An Intracellular Ammonium Transporter Is Necessary for Replication, Differentiation, and Resistance to Starvation and Osmotic Stress in <named-content content-type="genus-species">Trypanosoma cruzi</named-content>
    “... palindromic repeat analysis with Cas9 (CRISPR-Cas9) resulted in significant defects in epimastigote...”
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  12. 972
    Comparative genomic characterization of three Streptococcus parauberis strains in fish pathogen, as assessed by wide-genome analyses.
    “... through the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas system and which might...”
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  13. 973
    Decreased YAP activity reduces proliferative ability in human induced pluripotent stem cell of duchenne muscular dystrophy derived cardiomyocytes
    “..., and genome-edited (Ed)-DMD-iPSCs with in-frame (Ed-DMD-iPSCs) were created using CRISPR/Cas9. Nuclear...”
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  14. 974
    Reactivity of human AGO2 monoclonal antibody 11A9 with the SWI/SNF complex: A case study for rigorously defining antibody selectivity
    “... misleading results for ChIP, RNA-seq and Mass spectrometry. Therefore, we developed a CRISPR/Cas9 engineered...”
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  15. 975
    The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation
    “... to efficiently suppress α-syn aggregation. Here, we demonstrate that a CRISPR/Cas9-mediated knockout (KO) of a...”
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  16. 976
    Defects in autophagosome-lysosome fusion underlie Vici syndrome, a neurodevelopmental disorder with multisystem involvement
    “.... To investigate the function of EPG5, siRNA based EPG5 knock-down, and CRISPR/Cas9 mediated EPG5 knock-out HeLa...”
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  17. 977
    Effects of knocking out three anthocyanin modification genes on the blue pigmentation of gentian flowers
    “...Abstract Genome editing by the CRISPR/Cas9 system has recently been used to produce gene knockout...”
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  18. 978
    Chicken Interferon-induced Protein with Tetratricopeptide Repeats 5 Antagonizes Replication of RNA Viruses
    “...-stable chicken fibroblasts whereas CRISPR/Cas9-edited chIFIT5 gene knockout fibroblasts supported...”
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  19. 979
    Down-regulation of miR-214 reverses erlotinib resistance in non-small-cell lung cancer through up-regulating LHX6 expression
    “... overexpression, and the CRISPR-Cas9 system-mediated LHX6 knockdown reversed the reduction in the invasion...”
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  20. 980
    The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation
    “... or CRISPR-Cas9 mediated loss of function of mouse Nap1l3 and with overexpression of the gene, the number...”
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