Mostrando 81 - 100 Resultados de 1,137 Para Buscar '"CRISPR"', tiempo de consulta: 0.11s Limitar resultados
  1. 81
    Cas9 immunity creates challenges for CRISPR gene editing therapies
    “...Abstract Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 is a genome...”
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  2. 82
    CRISPR/Cpf1-mediated DNA-free plant genome editing
    “...Cpf1 is a type V CRISPR effector protein that has different target and guide RNA requirements...”
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  3. 83
    DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle
    “... assembly. Here, the authors use CRISPR-Cas9 and high-speed atomic force microscopy to ‘nanomap’ single...”
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  4. 84
    Combinatorial metabolic engineering using an orthogonal tri-functional CRISPR system
    “... sequentially in a high labor, low-throughput manner. Here, the authors use CRISPR-mediated gene activation...”
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  5. 85
    Contracting CAG/CTG repeats using the CRISPR-Cas9 nickase
    “..., the authors show that the CRISPR-Cas9 nuclease induces both expansions and contractions of the repeat region...”
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  6. 86
    Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila
    “...Applicability of CRISPR-Cas9 for in vivo screening has so far been limited. Here the authors...”
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  7. 87
    CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease
    “... to their prevention and cure. Here the authors present a CRISPR-based strategy that enhances the therapeutic potential...”
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  8. 88
    Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos
    “...Forward genetic approaches such as CRISPR screens are powerful ways to identify essential genes...”
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  9. 89
    Genome editing in maize directed by CRISPR–Cas9 ribonucleoprotein complexes
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  10. 90
    Enhancing the genome editing toolbox: genome wide CRISPR arrayed libraries
    “...Abstract CRISPR-Cas9 technology has accelerated biological research becoming routine for many...”
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  11. 91
    Detection of spacer precursors formed in vivo during primed CRISPR adaptation
    “...Primed adaptation in the CRISPR-Cas system helps recognition of previously encountered sequence...”
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  12. 92
    Tracing the transitions from pluripotency to germ cell fate with CRISPR screening
    “.... Here, the authors couple a novel compound reporter with CRISPR screening to identify key genes for exit...”
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  13. 93
    Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins
    Materias: “...CRISPR...”
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  14. 94
    Deletion of a Single LeishIF4E-3 Allele by the CRISPR-Cas9 System Alters Cell Morphology and Infectivity of <italic toggle="yes">Leishmania</italic>
    Materias: “...CRISPR...”
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  15. 95
    Pursuit of chlorovirus genetic transformation and CRISPR/Cas9-mediated gene editing.
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  16. 96
    Virus detection via programmable Type III-A CRISPR-Cas systems
    “...CRISPR-Cas based virus detection assays can be both rapid and sensitive. Here the authors use a...”
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  17. 97
    Generation of in situ CRISPR-mediated primary and metastatic cancer from monkey liver
    “... and metastatic liver tumors using the CRISPR/Cas9 in the adult cynomolgus monkey. Under ultrasound guidance...”
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  18. 98
    Machine learning based CRISPR gRNA design for therapeutic exon skipping.
    “... are transient oligonucleotide-based treatments that require frequent dosing. CRISPR-Cas9 based genome editing...”
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  19. 99
    CRISPR/Cas9-mediated gene targeting in Arabidopsis using sequential transformation
    “... sequential transformation method for CRISPR/Cas9-mediated gene targeting in Arabidopsis and demonstrate its...”
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  20. 100
    Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
    “...Control of CRISPR-Cas9 activity allows for fine-tuning of editing and gene expression. Here...”
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