Mostrando 1,081 - 1,100 Resultados de 1,137 Para Buscar '"CRISPR"', tiempo de consulta: 0.12s Limitar resultados
  1. 1081
    Loss of Septation Initiation Network (SIN) kinases blocks tissue invasion and unlocks echinocandin cidal activity against Aspergillus fumigatus.
    “... protein kinases required for survival under echinocandin stress, we employed CRISPR/Cas9-mediated gene...”
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  2. 1082
    Marine Sponges as <italic toggle="yes">Chloroflexi</italic> Hot Spots: Genomic Insights and High-Resolution Visualization of an Abundant and Diverse Symbiotic Clade
    “... of features relevant to symbiosis were further identified, including CRISPR-Cas systems, eukaryote-like repeat...”
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  3. 1083
    A highly prevalent SINE mutation in the myostatin (MSTN) gene promoter is associated with low circulating myostatin concentration in Thoroughbred racehorses
    “... and heterozygous MSTN-null horse embryos following CRISPR/Cas9 editing at the equine MSTN locus and nuclear...”
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  4. 1084
    Functional pre-therapeutic evaluation by genome editing of variants of uncertain significance of essential tumor suppressor genes
    “..., potential biomarkers of immunotherapy response, we developed a rapid functional assay based on CRISPR-Cas9...”
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  5. 1085
    Loss of Profilin3 Impairs Spermiogenesis by Affecting Acrosome Biogenesis, Autophagy, Manchette Development and Mitochondrial Organization
    “... vesicles during spermiogenesis, suggesting a role in vesicle transport for acrosome formation. Using CRISPR...”
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  6. 1086
    A Novel Spo11 Homologue Functions as a Positive Regulator in Cyst Differentiation in <i>Giardia lamblia</i>
    “.... Targeted disruption of <i>spo11</i> gene with CRISPR/Cas9 system led to a significant decrease in <i>cwp1-3...”
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  7. 1087
    The Fusion of <i>CLEC12A</i> and <i>MIR223HG</i> Arises from a <i>trans</i>-Splicing Event in Normal and Transformed Human Cells
    “...A</i> with the CRISPR/Cas9 Synergistic Activation Mediator (SAM) system increases <i>CLEC12A-MIR223...”
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  8. 1088
    Viruses in the Oceanic Basement
    “... palindromic repeat (CRISPR)-containing scaffolds in the metagenomes for which a taxonomy could be inferred...”
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  9. 1089
    Deficiency of ASGR1 in pigs recapitulates reduced risk factor for cardiovascular disease in humans
    “... the cardiovascular similarities between pigs and humans, we generated ASGR1-deficient pigs using the CRISPR/Cas9...”
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  10. 1090
    Staphylococcal Superantigens Stimulate Epithelial Cells through CD40 To Produce Chemokines
    “... of superantigens. We showed, through use of a CRISPR-Cas9 CD40 knockout, that the superantigens toxic shock...”
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  11. 1091
    TgPRELID, a Mitochondrial Protein Linked to Multidrug Resistance in the Parasite <named-content content-type="genus-species">Toxoplasma gondii</named-content>
    “... our hypothesis that TgPRELID mutations facilitate resistance to both I-BET151 and F3215-0002, CRISPR...”
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  12. 1092
    Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression
    “... of UCA1 and IGF2BP2 in CRC samples. CRISPR/Cas9 was employed to knockout (KO) UCA1, METTL3 and WTAP...”
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  13. 1093
    Intra-Tumoral Expression of SLC7A11 Is Associated with Immune Microenvironment, Drug Resistance, and Prognosis in Cancers: A Pan-Cancer Analysis
    “... on cell proliferation after the knockdown or knockout of SLC7A11 by either CRISPR or RNAi methods. Besides...”
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  14. 1094
    Comparison of SHANK3 deficiency in animal models: phenotypes, treatment strategies, and translational implications
    “... of new therapeutic approaches that target genetic haploinsufficiency, like CRISPR-mediated activation...”
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  15. 1095
    CdrS Is a Global Transcriptional Regulator Influencing Cell Division in <named-content content-type="genus-species">Haloferax volcanii</named-content>
    “... in the model archaeon Haloferax volcanii. The cdrS gene could not be deleted, but CRISPR interference (CRISPRi...”
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  16. 1096
    A New Model Trypanosomatid, <italic toggle="yes">Novymonas esmeraldas</italic>: Genomic Perception of Its “<italic toggle="yes">Candidatus</italic> Pandoraea novymonadis” Endosymbiont
    “... and CRISPR-Cas9-mediated approaches. IMPORTANCE Novymonas esmeraldas is a parasitic flagellate of the family...”
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  17. 1097
    Role of caveolin-1 as a biomarker for radiation resistance and tumor aggression in lung cancer.
    “... been observed to be highly expressed in radiation resistant A549 lung cancer cells. CRISPR-Cas9...”
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  18. 1098
    Size matters: Large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development.
    “... genes located within CN losses. Validation in zebrafish using CRISPR/Cas9 targeting confirmed...”
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  19. 1099
    The Impact of ZIP8 Disease-Associated Variants G38R, C113S, G204C, and S335T on Selenium and Cadmium Accumulations: The First Characterization
    “... using the CRISPR/Cas9 system. The elimination of ZIP8 expression was examined by PCR, DNA sequencing...”
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  20. 1100
    Hepatitis C Virus Indirectly Disrupts DNA Damage-Induced p53 Responses by Activating Protein Kinase R
    “... regularly interspaced short palindromic repeat (CRISPR)/Cas9-mediated ablation of double-stranded RNA (dsRNA...”
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