Comparison of SHANK3 deficiency in animal models: phenotypes, treatment strategies, and translational implications

par Jan Philipp Delling, Tobias M. Boeckers
Publié 2021

SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice

par Anne-Kathrin Lutz, Andrea Pérez Arévalo, Valentin Ioannidis, Nadine Stirmlinger, Maria Demestre, Richard Delorme, Thomas Bourgeron, Tobias M. Boeckers, Tobias M. Boeckers
Publié 2021

An SK3 channel/nWASP/Abi-1 complex is involved in early neurogenesis.

par Stefan Liebau, Julie Steinestel, Leonhard Linta, Alexander Kleger, Alexander Storch, Michael Schoen, Konrad Steinestel, Christian Proepper, Juergen Bockmann, Michael J Schmeisser, Tobias M Boeckers
Publié 2011

S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis

par Eleonora Daini, Simone Hagmeyer, Chiara A. De Benedictis, Joana S. Cristóvão, Martina Bodria, Aisling M. Ross, Andrea Raab, Tobias M. Boeckers, Joerg Feldmann, Cláudio M. Gomes, Michele Zoli, Antonietta Vilella, Andreas M. Grabrucker
Publié 2021

Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice

par Saša Peter, Michiel M. ten Brinke, Jeffrey Stedehouder, Claudia M. Reinelt, Bin Wu, Haibo Zhou, Kuikui Zhou, Henk-Jan Boele, Steven A. Kushner, Min Goo Lee, Michael J. Schmeisser, Tobias M. Boeckers, Martijn Schonewille, Freek E. Hoebeek, Chris I. De Zeeuw
Publié 2016

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro

par Caterina Prelli Bozzo, Rayhane Nchioua, Meta Volcic, Lennart Koepke, Jana Krüger, Desiree Schütz, Sandra Heller, Christina M. Stürzel, Dorota Kmiec, Carina Conzelmann, Janis Müller, Fabian Zech, Elisabeth Braun, Rüdiger Groß, Lukas Wettstein, Tatjana Weil, Johanna Weiß, Federica Diofano, Armando A. Rodríguez Alfonso, Sebastian Wiese, Daniel Sauter, Jan Münch, Christine Goffinet, Alberto Catanese, Michael Schön, Tobias M. Boeckers, Steffen Stenger, Kei Sato, Steffen Just, Alexander Kleger, Konstantin M. J. Sparrer, Frank Kirchhoff
Publié 2021

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation

par Marcel Naumann, Arun Pal, Anand Goswami, Xenia Lojewski, Julia Japtok, Anne Vehlow, Maximilian Naujock, René Günther, Mengmeng Jin, Nancy Stanslowsky, Peter Reinhardt, Jared Sterneckert, Marie Frickenhaus, Francisco Pan-Montojo, Erik Storkebaum, Ina Poser, Axel Freischmidt, Jochen H. Weishaupt, Karlheinz Holzmann, Dirk Troost, Albert C. Ludolph, Tobias M. Boeckers, Stefan Liebau, Susanne Petri, Nils Cordes, Anthony A. Hyman, Florian Wegner, Stephan W. Grill, Joachim Weis, Alexander Storch, Andreas Hermann
Publié 2018