Mostrando 1,101 - 1,120 Resultados de 1,137 Para Buscar '"CRISPR"', tiempo de consulta: 0.10s Limitar resultados
  1. 1101
    Dengue Virus Hijacks a Noncanonical Oxidoreductase Function of a Cellular Oligosaccharyltransferase Complex
    “... palindromic repeat (CRISPR) screen to identify host dependency factors required for DENV propagation...”
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  2. 1102
    Reduced Activity of Mutant Calcium-Dependent Protein Kinase 1 Is Compensated in <named-content content-type="genus-species">Plasmodium falciparum</named-content> through the Action of Protein Kinase G
    “... introduced into the CDPK1 locus using clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9...”
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  3. 1103
    Protein Kinase A Is Essential for Invasion of <named-content content-type="genus-species">Plasmodium falciparum</named-content> into Human Erythrocytes
    “..., CRISPR-Cas9 and conditional gene deletion (dimerizable cre) technologies were implemented to generate a P...”
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  4. 1104
    The Human Skin Double-Stranded DNA Virome: Topographical and Temporal Diversity, Genetic Enrichment, and Dynamic Associations with the Host Microbiome
    “... potential antibiotic resistance and virulence factors. CRISPR spacers identified in the bacterial DNA...”
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  5. 1105
    Genome-Resolved Metagenomics Extends the Environmental Distribution of the <italic toggle="yes">Verrucomicrobia</italic> Phylum to the Deep Terrestrial Subsurface
    “... CRISPR-Cas. To illuminate the phylogenetic and environmental distribution of these metabolic and adaptive...”
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  6. 1106
    Role of caveolin-1 as a biomarker for radiation resistance and tumor aggression in lung cancer
    “... been observed to be highly expressed in radiation resistant A549 lung cancer cells. CRISPR-Cas9...”
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  7. 1107
    Distributed hybrid-indexing of compressed pan-genomes for scalable and fast sequence alignment.
    “... in 575 minutes. BLASTing 189,864 Crispr-Cas9 gRNA target sequences (23 MB in total) to the compressed...”
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  8. 1108
    Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection.
    “..., was not directly responsible for this, as an independently-generated CRISPR/Cas9 Card19 knockout mouse line (Card19...”
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  9. 1109
    Hepatocyte-specific TM6SF2 knockout aggravates hepatic steatosis in mice with nonalcoholic fatty liver disease
    por ZHANG Jie
    Publicado 2021
    “... the role of TM6SF2 in the development of nonalcoholic fatty liver disease (NAFLD). MethodsThe CRISPR/Cas9...”
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  10. 1110
    Red- and Blue-Light Sensing in the Plant Pathogen <named-content content-type="genus-species">Alternaria alternata</named-content> Depends on Phytochrome and the White-Collar Protein LreA
    “... protein (MAP) kinase pathway. We created loss-of function mutations for fphA, lreA, and hogA using CRISPR...”
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  11. 1111
    Time-Resolved Transposon Insertion Sequencing Reveals Genome-Wide Fitness Dynamics during Infection
    “... regularly interspaced short palindromic repeats with Cas9 (CRISPR/Cas9)....”
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  12. 1112
    The ClpX and ClpP2 Orthologs of <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Perform Discrete and Essential Functions in Organism Growth and Development
    “... CRISPR interference led to a decrease in bacterial growth, and this effect was complemented in trans by a...”
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  13. 1113
    The Long Noncoding RNA <italic toggle="yes">HEAL</italic> Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter
    “..., HEAL knockdown and knockout mediated by RNA interference (RNAi) and CRISPR-Cas9, respectively, prevent...”
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  14. 1114
    Charge-Mediated Pyrin Oligomerization Nucleates Antiviral IFI16 Sensing of Herpesvirus DNA
    “... never been explored. Our integrative quantitative proteomics, molecular CRISPR/Cas9-based assays...”
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  15. 1115
    Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection
    “... are resistant to HuNoV replication. To evaluate the role of FUT2 in HuNoV replication, we used CRISPR...”
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  16. 1116
    IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of <named-content content-type="genus-species">Legionella pneumophila</named-content>
    “..., partially reduced IFN-γ-mediated restriction of L. pneumophila. Further, using a combinatorial CRISPR/Cas9...”
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  17. 1117
    Werner Helicase Control of Human Papillomavirus 16 E1-E2 DNA Replication Is Regulated by SIRT1 Deacetylation
    “...-replicating DNA. CRISPR/Cas9 editing demonstrates that WRN, like SIRT1, regulates the quantity and fidelity...”
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  18. 1118
    Combined and Distinct Roles of Agr Proteins in <named-content content-type="genus-species">Clostridioides difficile</named-content> 630 Sporulation, Motility, and Toxin Production
    “... system has multiple functions, not all of which depend on AgrB1. CRISPR-Cas9n deletion of agrB1, agrD1...”
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  19. 1119
    Identification of Restriction Factors by Human Genome-Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L<sup>−</sup>C7L<sup>−</sup> Mutant
    “...6. Moreover, SAMD9 and WDR6 clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9...”
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  20. 1120
    Werner Syndrome Protein (WRN) Regulates Cell Proliferation and the Human Papillomavirus 16 Life Cycle during Epithelial Differentiation
    “.... We CRISPR/Cas9 edited N/Tert-1 and N/Tert-1+HPV16 cells to knock out WRN protein expression...”
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