Mostrando 161 - 180 Resultados de 1,137 Para Buscar '"CRISPR"', tiempo de consulta: 0.04s Limitar resultados
  1. 161
    CRISPR-Cas immunity against phages: its effects on the evolution and survival of bacterial pathogens.
    por Luciano A Marraffini
    Publicado 2013
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  2. 162
    Protocol for assessment of the efficiency of CRISPR/Cas RNP delivery to different types of target cells
    “...<h4>Background</h4> Delivery of CRISPR/Cas RNPs to target cells still remains the biggest...”
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  3. 163
    A Universal, Genomewide GuideFinder for CRISPR/Cas9 Targeting in Microbial Genomes
    Materias: “...CRISPR...”
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  4. 164
    Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair
    “.... Here, the authors use a pooled CRISPR screen to identify inhibition of CDC7 as a strategy to improve...”
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  5. 165
    A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system
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  6. 166
    A redox-based electrogenetic CRISPR system to connect with and control biological information networks
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  7. 167
    Multi-functional genome-wide CRISPR system for high throughput genotype–phenotype mapping
    “... such as overexpression, repression or deletion. Here the authors present a tri-functional CRISPR system that can engineer...”
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  8. 168
    Live-cell imaging of circadian clock protein dynamics in CRISPR-generated knock-in cells
    “... use CRISPR gene editing mediated knock-in to fluorescently tag Per2 and Cry1, and study cellular...”
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  9. 169
    Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens
    “...CRISPR/Cas9-mediated forward genetic screens and gene-trap mutagenesis screens in haploid cells...”
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  10. 170
    Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs
    “... biology, and CRISPR-Cas9 is one of the tools being developed to achieve that goal. Here the authors...”
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  11. 171
    Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system
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  12. 172
    Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6
    “...Upon target RNA recognition, type III CRISPR-Cas systems produce cyclic oligoadenylates...”
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  13. 173
    Nrl knockdown by AAV-delivered CRISPR/Cas9 prevents retinal degeneration in mice
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  14. 174
    Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression
    “...CRISPR-Cas9 has been utilized to screen the genome in loss-of-function studies to identify genetic...”
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  15. 175
    Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex
    “... CRISPR sequences from RNA and DNA substrates....”
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  16. 176
    Efficient labeling and imaging of protein-coding genes in living cells using CRISPR-Tag
    “... the authors present CRISPR-Tag, which marks genes of interest with small repeat sequences to recruit dCas9-GFP....”
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  17. 177
    Incorporation of bridged nucleic acids into CRISPR RNAs improves Cas9 endonuclease specificity
    “...Minimizing off-target effects is an important concern for therapeutic applications of CRISPR-Cas9...”
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  18. 178
    Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1
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  19. 179
    Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity
    “...CRISPR-Cas9 has been widely used to manipulate genomes, however control over activity is necessary...”
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  20. 180
    Publisher Correction: Tracing the transitions from pluripotency to germ cell fate with CRISPR screening
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