Nonsex genes in the mating type locus of Candida albicans play roles in a/α biofilm formation, including impermeability and fluconazole resistance.

por Thyagarajan Srikantha, Karla J Daniels, Claude Pujol, Nidhi Sahni, Song Yi, David R Soll
Publicado 2012

Relacin, a novel antibacterial agent targeting the Stringent Response.

por Ezequiel Wexselblatt, Yaara Oppenheimer-Shaanan, Ilana Kaspy, Nir London, Ora Schueler-Furman, Eylon Yavin, Gad Glaser, Joshua Katzhendler, Sigal Ben-Yehuda
Publicado 2012

Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells.

por Hiromichi Dansako, Daisuke Yamane, Christoph Welsch, David R McGivern, Fengyu Hu, Nobuyuki Kato, Stanley M Lemon
Publicado 2013

The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways.

por Jacob G Malone, Tina Jaeger, Pablo Manfredi, Andreas Dötsch, Andrea Blanka, Raphael Bos, Guy R Cornelis, Susanne Häussler, Urs Jenal
Publicado 2012

Targeting iron acquisition blocks infection with the fungal pathogens Aspergillus fumigatus and Fusarium oxysporum.

por Sixto M Leal, Sanhita Roy, Chairut Vareechon, Steven deJesus Carrion, Heather Clark, Manuel S Lopez-Berges, Antonio Di Pietro, Marcus Schrettl, Nicola Beckmann, Bernhard Redl, Hubertus Haas, Eric Pearlman
Publicado 2013

Exhausted cytotoxic control of Epstein-Barr virus in human lupus.

por Martin Larsen, Delphine Sauce, Claire Deback, Laurent Arnaud, Alexis Mathian, Makoto Miyara, David Boutolleau, Christophe Parizot, Karim Dorgham, Laura Papagno, Victor Appay, Zahir Amoura, Guy Gorochov
Publicado 2011

The ESCRT machinery is recruited by the viral BFRF1 protein to the nucleus-associated membrane for the maturation of Epstein-Barr Virus.

por Chung-Pei Lee, Po-Ting Liu, Hsiu-Ni Kung, Mei-Tzu Su, Huey-Huey Chua, Yu-Hsin Chang, Chou-Wei Chang, Ching-Hwa Tsai, Fu-Tong Liu, Mei-Ru Chen
Publicado 2012

A peptidoglycan fragment triggers β-lactam resistance in Bacillus licheniformis.

por Ana Amoroso, Julien Boudet, Stéphanie Berzigotti, Valérie Duval, Nathalie Teller, Dominique Mengin-Lecreulx, André Luxen, Jean-Pierre Simorre, Bernard Joris
Publicado 2012

EphrinA2 regulates clathrin mediated KSHV endocytosis in fibroblast cells by coordinating integrin-associated signaling and c-Cbl directed polyubiquitination.

por Dipanjan Dutta, Sayan Chakraborty, Chirosree Bandyopadhyay, Mohanan Valiya Veettil, Mairaj Ahmed Ansari, Vivek Vikram Singh, Bala Chandran
Publicado 2013

Membrane damage during Listeria monocytogenes infection triggers a caspase-7 dependent cytoprotective response.

por Sara K B Cassidy, Jon A Hagar, Thirumala Devi Kanneganti, Luigi Franchi, Gabriel Nuñez, Mary X D O'Riordan
Publicado 2012

Directly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latency.

por Matthew J Pace, Erin H Graf, Luis M Agosto, Angela M Mexas, Frances Male, Troy Brady, Frederic D Bushman, Una O'Doherty
Publicado 2012

MHC class I bound to an immunodominant Theileria parva epitope demonstrates unconventional presentation to T cell receptors.

por Isabel K Macdonald, Maria Harkiolaki, Lawrence Hunt, Timothy Connelley, A Victoria Carroll, Niall D MacHugh, Simon P Graham, E Yvonne Jones, W Ivan Morrison, Darren R Flower, Shirley A Ellis
Publicado 2010

Introducing the outbreak threshold in epidemiology.

por Matthew Hartfield, Samuel Alizon
Publicado 2013

Conditional Stat1 ablation reveals the importance of interferon signaling for immunity to Listeria monocytogenes infection.

por Elisabeth Kernbauer, Verena Maier, Dagmar Stoiber, Birgit Strobl, Christine Schneckenleithner, Veronika Sexl, Ursula Reichart, Boris Reizis, Ulrich Kalinke, Amanda Jamieson, Mathias Müller, Thomas Decker
Publicado 2012

Acid stability of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity.

por Rebecca M DuBois, Hassan Zaraket, Muralidhar Reddivari, Richard J Heath, Stephen W White, Charles J Russell
Publicado 2011

Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.

por Edel A McNeela, Aine Burke, Daniel R Neill, Cathy Baxter, Vitor E Fernandes, Daniela Ferreira, Sarah Smeaton, Rana El-Rachkidy, Rachel M McLoughlin, Andres Mori, Barry Moran, Katherine A Fitzgerald, Jurg Tschopp, Virginie Pétrilli, Peter W Andrew, Aras Kadioglu, Ed C Lavelle
Publicado 2010

Immune subversion and quorum-sensing shape the variation in infectious dose among bacterial pathogens.

por João Alves Gama, Sophie S Abby, Sara Vieira-Silva, Francisco Dionisio, Eduardo P C Rocha
Publicado 2012

Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3.

por Marcelo Marcet-Palacios, Brenda Lee Duggan, Irene Shostak, Michele Barry, Tracy Geskes, John A Wilkins, Akiko Yanagiya, Nahum Sonenberg, R Chris Bleackley
Publicado 2011

Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1.

por Malte Bachmann, Katharina Horn, Ina Rudloff, Itamar Goren, Martin Holdener, Urs Christen, Nicole Darsow, Klaus-Peter Hunfeld, Ulrike Koehl, Peter Kind, Josef Pfeilschifter, Peter Kraiczy, Heiko Mühl
Publicado 2010

Molecular and evolutionary bases of within-patient genotypic and phenotypic diversity in Escherichia coli extraintestinal infections.

por Maxime Levert, Oana Zamfir, Olivier Clermont, Odile Bouvet, Sylvain Lespinats, Marie Claire Hipeaux, Catherine Branger, Bertrand Picard, Claude Saint-Ruf, Françoise Norel, Thierry Balliau, Michel Zivy, Hervé Le Nagard, Stéphane Cruveiller, Béatrice Chane-Woon-Ming, Susanna Nilsson, Ivana Gudelj, Katherine Phan, Thomas Ferenci, Olivier Tenaillon, Erick Denamur
Publicado 2010