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  1. 6021
    Pleckstrin-2 is essential for erythropoiesis in β-thalassemic mice, reducing apoptosis and enhancing enucleation
    “... in β-thalassemic mice by reducing cofilin-mediated apoptosis and enhancing enucleation by activating...”
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  2. 6022
    NLRP11 attenuates Toll-like receptor signalling by targeting TRAF6 for degradation via the ubiquitin ligase RNF19A
    “... is an inhibitory protein that targets TRAF6 for K48 ubiquitination-mediated proteasomal degradation to limit...”
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  3. 6023
    Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions
    “...The basement membrane is located at tissue interfaces, but how it mediates distinct inter-tissue...”
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  4. 6024
    Cholinergic midbrain afferents modulate striatal circuits and shape encoding of action strategies
    “...Acetylcholine (ACh) in the striatum is involved in mediating action flexibility. Here the authors...”
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  5. 6025
    Type I interferon sensing unlocks dormant adipocyte inflammatory potential
    “...White adipose inflammation can occur in obesity and is at least in part mediated by inflammatory...”
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  6. 6026
    Pathways for horizontal gene transfer in bacteria revealed by a global map of their plasmids
    “...Plasmids can mediate gene transfer across bacterial populations. Here, the authors describe a...”
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  7. 6027
    Ultrafast nonlinear optical response of Dirac fermions in graphene
    “... of the quantum dynamics of Dirac carriers mediating the material’s nonlinear response....”
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  8. 6028
    Co-transmission of acetylcholine and GABA regulates hippocampal states
    “...Acetylcholine (ACh) release in the central nervous system is thought to be unitary and mediated non...”
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  9. 6029
    STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment
    “... STING-mediated paracrine signaling pathway....”
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  10. 6030
    Act1 is a negative regulator in T and B cells via direct inhibition of STAT3
    “...Adaptor for IL-17 receptors (Act1) is known to be crucial for IL-17-mediated immune responses. Here...”
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  11. 6031
    Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence
    “... and activation through CUX1-mediated transactivation of ADAM17....”
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  12. 6032
    Electrically reversible cracks in an intermetallic film controlled by an electric field
    “.... Liu et al. use an intermetallic alloy and ferroelectric oxide junction to mediate the reversible...”
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  13. 6033
    Superior colliculus modulates cortical coding of somatosensory information
    “... by the superior colliculus is mediated via a powerful di-synaptic pathway through the thalamus....”
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  14. 6034
    Flexible supercapacitor electrodes based on real metal-like cellulose papers
    “...With ligand-mediated layer-by-layer assembly between metal nanoparticles and small organic...”
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  15. 6035
    A brain-wide functional map of the serotonergic responses to acute stress and fluoxetine
    “... nucleus. Here, the authors use optogenetics and fMRI mediated mapping of the mouse brain-wide serotonin...”
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  16. 6036
    Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation
    “...The proteasome plays a key role in proteostasis by mediating the degradation of ubiquitinated...”
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  17. 6037
    Biased genome editing using the local accumulation of DSB repair molecules system
    “... to microhomology-mediated end-joining....”
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  18. 6038
    Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
    “...SOCS3 is an important negative feedback inhibitor of JAK–STAT-mediated cytokine signalling. Here...”
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  19. 6039
    Lateral inhibition by Martinotti interneurons is facilitated by cholinergic inputs in human and mouse neocortex
    “...Parvalbumin and somatostatin expressing interneurons mediate lateral inhibition between cortical...”
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  20. 6040
    Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 infection
    “.... The authors describe that SARS-COV-2 can directly infect human kidney, possibly mediating tubular pathogenesis....”
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