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  1. 6401
    Bacterial viruses enable their host to acquire antibiotic resistance genes from neighbouring cells
    “... their host cells. Here, Haaber et al. show that these viral particles can mediate the transfer of antibiotic...”
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  2. 6402
    Inactivation of nuclear GSK3β by Ser389 phosphorylation promotes lymphocyte fitness during DNA double-strand break response
    “..., protecting the activated lymphocytes from necroptosis-mediated cell death....”
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  3. 6403
    Microtubule-dependent balanced cell contraction and luminal-matrix modification accelerate epithelial tube fusion
    “... and then fuse their plasma membranes. Here the authors show that a balanced pulling force mediated by myosin...”
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  4. 6404
    The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance
    “... the crucial role of AMPK for cellular stresses and growth factors- mediated Akt activation through a mechanism...”
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  5. 6405
    Tamoxifen therapy in a murine model of myotubular myopathy
    “..., and that the effect is mediated via estrogen receptor signaling and involves modulation of DNM2 expression....”
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  6. 6406
    CDK1 dependent phosphorylation of hTERT contributes to cancer progression
    “..., the authors show that hTERT is phosphorylated by CDK1 and that this event is necessary for hTERT-mediated RNA...”
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  7. 6407
    A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia
    “..., unraveling potential molecular mediators influencing AP induced hyperphagia in mouse models....”
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  8. 6408
    Insulin/Snail1 axis ameliorates fatty liver disease by epigenetically suppressing lipogenesis
    “... lipogenesis by repressing Fasn expression but insulin-mediated Snail1 upregulation is impaired during obesity...”
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  9. 6409
    The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice
    “... AID-mediated target depletion in mice....”
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  10. 6410
    I(nsp1)ecting SARS-CoV-2–ribosome interactions
    “...-mediated translation inhibition and how Nsp1 inhibition could impact host immune responses and suppress...”
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  11. 6411
    Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis
    “..., mediates nitrogen distribution, and is important for virulence during infection of macrophages and mice....”
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  12. 6412
    Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family
    “...Cellular uptake of transition metal ions is mediated by members of the SLC11/NRAMP family. Here...”
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  13. 6413
    Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma
    “... that expression of ADAR1 correlates with poor patient outcomes, and that ADAR1-mediated editing of GLI1 is a...”
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  14. 6414
    Activity-dependent isomerization of Kv4.2 by Pin1 regulates cognitive flexibility
    “... function. Here, the authors describe Pin1-mediated regulation of the Kv4.2 complex, which impacts reversal...”
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  15. 6415
    Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria
    “...Bcl-2 interacting killer (Bik) decreases airway epithelial hyperplasia via apoptosis mediated...”
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  16. 6416
    Chemoselective synthesis and analysis of naturally occurring phosphorylated cysteine peptides
    “...Protein phosphorylation mediates signalling and other important cellular processes...”
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  17. 6417
    Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program
    “... of an antiviral program mediated by the activation of the host transcription factor NRF2....”
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  18. 6418
    A rapid access to aliphatic sulfonyl fluorides
    “..., the authors report a mild visible light-mediated decarboxylative fluorosulfonylethylation for the synthesis...”
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  19. 6419
    Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction
    “... occur co-translationally. Here the authors identify elements of yeast Ssb (Hsp70) that mediate ribosomal...”
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  20. 6420
    Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos
    “... for sgRNA design and a recombination-mediated cassette system for delivery into mosquito cell lines....”
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