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  1. 6461
    MICU1 drives glycolysis and chemoresistance in ovarian cancer
    “... Ca2+-mediated regulation of pyruvate dehydrogenase activity that results in increased glycolysis....”
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  2. 6462
    RHOA signaling defects result in impaired axon guidance in iPSC-derived neurons from patients with tuberous sclerosis complex
    “...-independent RhoA signaling-mediated axon guidance....”
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  3. 6463
    CUT&Tag for efficient epigenomic profiling of small samples and single cells
    “... of cells at high resolution. Here the authors describe CUT&Tag, which uses antibody-mediated tethering...”
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  4. 6464
    Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response
    “...- mediated type 1 interferon response induction in the lungs....”
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  5. 6465
    Sensory TRP channels contribute differentially to skin inflammation and persistent itch
    “..., but it is not known if these are mediated by shared signaling pathways. The authors show that persistent itch requires...”
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  6. 6466
    Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus
    “...Wnt proteins mediate embryonic development but how protein localization and patterning is regulated...”
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  7. 6467
    Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation
    “...The protease Atg4 mediates Atg8 lipidation, required for autophagosome biogenesis, but also...”
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  8. 6468
    Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
    “... resistance through a low-density lipoprotein receptor-related protein−2 mediated mechanism in mice....”
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  9. 6469
    Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia
    “...)-mediated signalling of neoplastic B lymphocytes. Here the authors unveil the structural basis and diversity...”
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  10. 6470
    Emr1 regulates the number of foci of the endoplasmic reticulum-mitochondria encounter structure complex
    “... be mediated with the ER-mitochondria encounter structure (ERMES) complex, though precise regulation is unclear...”
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  11. 6471
    Asymmetric ephaptic inhibition between compartmentalized olfactory receptor neurons
    “...) interactions mediate lateral inhibition between ORNs, with physically larger ORNs dominating ephaptic...”
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  12. 6472
    Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions
    “... and accompanying data suggest that distinct affinities of TNF ligand for its receptors mediate non-redundant...”
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  13. 6473
    SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis
    “... SMAD4-mediated breast cancer metastasis providing a possible therapeutic avenue....”
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  14. 6474
    Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding
    “...-mediated refolding....”
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  15. 6475
    Degradation of blue-phosphorescent organic light-emitting devices involves exciton-induced generation of polaron pair within emitting layers
    “... of the degradation that involves exciton-mediated electron transfer as a key step for the generation of radical ion...”
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  16. 6476
    Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly
    “... directly interacts with STIL and mediates efficient centriolar targeting of STIL, PLK4 activation...”
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  17. 6477
    Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314
    “... induced in mice by methicillin-resistant Staphylococcus aureus infection is mediated by bacterial pore...”
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  18. 6478
    Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth
    “... increased tumor growth in XO ki mice, via macrophage-mediated immunoregulatory responses....”
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  19. 6479
    Calcium is an essential cofactor for metal efflux by the ferroportin transporter family
    “... into blood circulation, but the molecular mechanisms of Fpn-mediated iron transport remain obscure. Here...”
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  20. 6480
    Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation
    “... of function experiments to demonstrate that FGF signalling mediated trophectoderm morphogenesis orchestrates...”
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