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  1. 11161
    LNA/DNA mixmer-based antisense oligonucleotides correct alternative splicing of the SMN2 gene and restore SMN protein expression in type 1 SMA fibroblasts
    “... in the exon 7. One of the most promising strategies to treat SMA is antisense oligonucleotide (AON)-mediated...”
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  2. 11162
    Engineering of an angiogenic niche by perfusion culture of adipose-derived stromal vascular fraction cells
    “... ectopic implantation. This was likely mediated by pericytes, whose number was significantly higher (4.5...”
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  3. 11163
    Genome-wide survey indicates diverse physiological roles of the barley (Hordeum vulgare L.) calcium-dependent protein kinase genes
    “... CDPKs may be involved in mediating cross-talk among different signalling pathways. Our data provide...”
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  4. 11164
    Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts
    “... of which transporters mediate the specific uptake of TKIs in target cells and of how the expression...”
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  5. 11165
    Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development
    “...-Cre-mediated, pancreatic PAK4 gene depletion in the mouse, verified by loss of PAK4 protein expression...”
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  6. 11166
    Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells
    “... the Dextran-Catechin potent antiangiogenic activity is mediated by disrupting copper homeostasis. Thus...”
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  7. 11167
    The CsHSP17.2 molecular chaperone is essential for thermotolerance in Camellia sinensis
    “... may act as a molecular chaperone to mediate heat tolerance by maintaining maximum photochemical...”
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  8. 11168
    Transcriptome profiling of mouse colonic eosinophils reveals a key role for eosinophils in the induction of s100a8 and s100a9 in mucosal healing
    “.... Although eosinophils express and synthesize a plethora of proteins that can mediate their effector...”
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  9. 11169
    Use-dependent potentiation of voltage-gated calcium channels rescues neurotransmission in nerve terminals intoxicated by botulinum neurotoxin serotype A
    “...) underlies 3,4-diaminopyridine (3,4-DAP)-mediated rescue of neurotransmission in central nervous system...”
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  10. 11170
    Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice
    “... demonstrated that activation of ALOX15/13-HODE circuit critically mediates the pathogenesis of ALD. This study...”
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  11. 11171
    Plasma GDF15 level is elevated in psychosis and inversely correlated with severity
    “... mediated functionality in severe psychosis. Study replication in larger cohorts will be necessary to assess...”
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  12. 11172
    miR-301b~miR-130b—PPARγ axis underlies the adipogenic capacity of mesenchymal stem cells with different tissue origins
    “... associated with MSCs-mediated abnormal adipogenesis....”
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  13. 11173
    Human esophageal myofibroblast secretion of bone morphogenetic proteins and GREMLIN1 and paracrine regulation of squamous epithelial growth
    “... (BMP) signaling and to paracrine mediated epithelial-mesenchymal interactions in the human esophagus...”
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  14. 11174
    Global ubiquitination analysis reveals extensive modification and proteasomal degradation of cowpox virus proteins, but preservation of viral cores
    “..., suggesting that uncoating is mediated by proteasomal degradation of viral core proteins. Although...”
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  15. 11175
    Virus and dsRNA-triggered transcriptional responses reveal key components of honey bee antiviral defense
    “... the role of a non-sequence specific dsRNA-mediated antiviral pathway....”
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  16. 11176
    Honokiol inhibits ultraviolet radiation-induced immunosuppression through inhibition of ultraviolet-induced inflammation and DNA hypermethylation in mouse skin
    “... preventive effect on UVB-induced suppression of the CHS response. The inflammatory mediators, COX-2 and PGE2...”
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  17. 11177
    Heterologous expression of the yeast Tpo1p or Pdr5p membrane transporters in Arabidopsis confers plant xenobiotic tolerance
    “... are able to mediate resistance to a broad range of compounds of agricultural interest in yeast as well...”
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  18. 11178
    Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis
    “...90; secondly, an atypical unfolded protein response (UPR) linked to the Ipom-F-mediated perturbation...”
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  19. 11179
    Evolution of the rodent Trim5 cluster is marked by divergent paralogous expansions and independent acquisitions of TrimCyp fusions
    “..., is a retroviral restriction factor that mediates a post-entry block to infection. Previous studies...”
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  20. 11180
    Genome-wide identification and expression analyses of genes involved in raffinose accumulation in sesame
    “... together, these results shed light on the RFOs-mediated abiotic stress resistance in sesame and provide a...”
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