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  1. 16281
    CD4<sup>+</sup> T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during <italic toggle="yes">Cryptococcus neoformans</italic> Meningoencephalitis
    “... cells critically mediates CNS injury and mortality. This model demonstrates that antifungal immune...”
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  2. 16282
    RIP1, RIP3, and MLKL Contribute to Cell Death Caused by <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin
    “... CPE-mediated diseases....”
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  3. 16283
    Mutations in the <named-content content-type="genus-species">Borrelia burgdorferi</named-content> Flagellar Type III Secretion System Genes <italic toggle="yes">fliH</italic> and <italic toggle="yes">fliI</italic> Profoundly Affect Spirochete Flagellar Assembly, Morphology, Motility, Structure, and Cell Division
    “... cytoplasmic proteins that play important roles in the type III secretion system (T3SS)-mediated export...”
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  4. 16284
    Targeting <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Tumor Necrosis Factor Alpha-Downregulating Genes for the Development of Antituberculous Vaccines
    “... host cell TNF production. This study identified M. tuberculosis genes that can mediate inhibition...”
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  5. 16285
    EspC, an Autotransporter Protein Secreted by Enteropathogenic <named-content content-type="genus-species">Escherichia coli</named-content>, Causes Apoptosis and Necrosis through Caspase and Calpain Activation, Including Direct Procaspase-3 Cleavage
    “... the role of EspC in cell death induced by EPEC. EspC is involved in EPEC-mediated cell death and induces...”
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  6. 16286
    Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection
    “... regularly interspaced short palindromic repeat (CRISPR)/Cas9-mediated knockouts in primary fibroblasts...”
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  7. 16287
    <named-content content-type="genus-species">Staphylococcus aureus</named-content> Leukocidin LukED and HIV-1 gp120 Target Different Sequence Determinants on CCR5
    “... to mediate cytotoxicity and virus entry. These analyses showed that the second and third extracellular loops...”
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  8. 16288
    Functional Analysis of the Human Antibody Response to Meningococcal Factor H Binding Protein
    “...-purified serum anti-FHbp antibodies elicited human complement-mediated bactericidal activity...”
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  9. 16289
    Targeting Alpha Toxin and ClfA with a Multimechanistic Monoclonal-Antibody-Based Approach for Prophylaxis of Serious <named-content content-type="genus-species">Staphylococcus aureus</named-content> Disease
    “... combination targeting alpha toxin (AT) and clumping factor A (ClfA) that neutralizes AT-mediated cytotoxicity...”
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  10. 16290
    Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection
    “... was required for MRSA clearance, whereas IFN-α signaling late in infection was not, though it did mediate...”
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  11. 16291
    The ClpX and ClpP2 Orthologs of <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Perform Discrete and Essential Functions in Organism Growth and Development
    “... turnover, and we hypothesize that proteases are critical for mediating differentiation. The Clp protease...”
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  12. 16292
    <named-content content-type="genus-species">Toxoplasma gondii</named-content> Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Orchestrate Chronic Infection and GRA12 Underpins Resistance to Host Gamma Interferon
    “...-γ-activated host cell innate immunity. Our findings uncover a key role for GRA12 in mediating...”
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  13. 16293
    Live-Cell FRET Reveals that Malaria Nutrient Channel Proteins CLAG3 and RhopH2 Remain Associated throughout Their Tortuous Trafficking
    “...) mediates this uptake and is linked to the parasite-encoded RhopH complex, consisting of CLAG3, RhopH2...”
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  14. 16294
    The Long Noncoding RNA <italic toggle="yes">HEAL</italic> Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter
    “..., HEAL knockdown and knockout mediated by RNA interference (RNAi) and CRISPR-Cas9, respectively, prevent...”
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  15. 16295
    <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Quorum Sensing Molecule Alters Skeletal Muscle Protein Homeostasis by Perturbing the Antioxidant Defense System
    “...-mediated skeletal muscle dysfunction caused by P. aeruginosa. IMPORTANCE Pseudomonas aeruginosa, a...”
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  16. 16296
    <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Regulatory Protein AnvM Controls Pathogenicity in Anaerobic Environments and Impacts Host Defense
    “... the mechanisms of PA3880-mediated regulation in virulence, we utilized a bacterial two-hybrid assay and found...”
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  17. 16297
    <named-content content-type="genus-species">Staphylococcus aureus</named-content> ATP Synthase Promotes Biofilm Persistence by Influencing Innate Immunity
    “... on their antibiotic tolerance and ability to evade immune-mediated clearance. The virulence determinants responsible...”
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  18. 16298
    Endogenous Viral Element-Derived Piwi-Interacting RNAs (piRNAs) Are Not Required for Production of Ping-Pong-Dependent piRNAs from Diaphorina citri Densovirus
    por Jared C. Nigg, Yen-Wen Kuo, Bryce W. Falk
    Publicado 2020
    “... of this DNA virus did not require endogenous piRNAs and that endogenous piRNAs did not mediate targeting...”
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  19. 16299
    <named-content content-type="genus-species">Toxoplasma gondii</named-content> Superinfection and Virulence during Secondary Infection Correlate with the Exact <italic toggle="yes">ROP5/ROP18</italic> Allelic Combination
    “... host effectors that mediate parasite killing, were required for these phenotypes. We speculate...”
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  20. 16300
    The Eng1 β-Glucanase Enhances <italic toggle="yes">Histoplasma</italic> Virulence by Reducing β-Glucan Exposure
    “... virulence in vivo, particularly during the cell-mediated immunity stage. Histoplasma yeasts deficient...”
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