Mostrando 1 - 20 Resultados de 114 Para Buscar '"RAC1"', tiempo de consulta: 0.21s Limitar resultados
  1. 1
    Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration
    “...The small GTPase Rac1 regulates various cellular processes, including cell migration. However, Rac1...”
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  2. 2
    Serine-71 phosphorylation of Rac1 modulates downstream signaling.
    “...The Rho GTPases Rac1 and Cdc42 regulate a variety of cellular functions by signaling to different...”
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  3. 3
    Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1
    “... regulator Rac1. Furthermore, Rac1 inhibition had a direct, protective effect on podocyte barrier function...”
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  4. 4
    Optogenetic dissection of Rac1 and Cdc42 gradient shaping
    “...A steep gradient of Cdc42 is at the front of migrating cells, whereas the active Rac1 gradient...”
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  5. 5
    Characterization of the erythrocyte GTPase Rac1 in relation to Plasmodium falciparum invasion
    “... erythrocyte proteins involved in this process have been identified so far. The erythrocyte protein Rac1 is a...”
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  6. 6
    Rac1 dynamics in the human opportunistic fungal pathogen Candida albicans.
    “...The small Rho G-protein Rac1 is highly conserved from fungi to humans, with approximately 65...”
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  7. 7
    Regulation of Rac1 transcription by histone and DNA methylation in diabetic retinopathy
    “... for Nox2 activation, Rac1, is also transcriptionally activated via active DNA methylation...”
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  8. 8
    Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions
    “... reduction of RAC1 prenylation increase RAC1 interaction with the adaptor protein IQGAP1, leading to GTP...”
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  9. 9
    RAC1 Activation as a Potential Therapeutic Option in Metastatic Cutaneous Melanoma
    Materias: “...RAC1...”
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  10. 10
    Activation of a Ductal-to-Endocrine Transdifferentiation Transcriptional Program in the Pancreatic Cancer Cell Line PANC-1 Is Controlled by RAC1 and RAC1b through Antagonistic Regulation of Stemness Factors
    “... of the small GTPase RAC1. Ectopic expression in PANC-1 cells of dominant negative or constitutively active...”
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  11. 11
    Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent.
    “...Endothelial cell migration is an essential aspect of tumor angiogenesis. Rac1 activity is needed...”
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  12. 12
    Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease.
    “...Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control...”
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  13. 13
    Tiam1/Rac1 complex controls Il17a transcription and autoimmunity
    “...Tiam1 is a guanine nucleotide exchange factor for the Rho-family GTPase Rac1. Here, the authors...”
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  14. 14
    The interplay of Rac1 activity, ubiquitination and GDI binding and its consequences for endothelial cell spreading.
    “...Signaling by the Rho GTPase Rac1 is key to the regulation of cytoskeletal dynamics, cell spreading...”
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  15. 15
    RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways
    “...RAC1 is a downstream target of the Wnt signaling that promotes intestinal stem cell expansion...”
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  16. 16
    Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics
    “...Abstract The small-GTPase Rac1 is a key molecular regulator linking extracellular signals to actin...”
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  17. 17
    Rac1 activates non-oxidative pentose phosphate pathway to induce chemoresistance of breast cancer
    “.... Here, the authors show that Rac1 increases glycolysis and non-oxidative pentose phosphate pathway...”
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  18. 18
    Author Correction: Regulation of local GTP availability controls RAC1 activity and cell invasion
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  19. 19
    STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap
    “... understood. Here, the authors find that an activator of the Rac1 GTPase, STEF/TIAM2, localises to the nuclear...”
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  20. 20
    Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1.
    “...-actin at cell-cell junctions. We thus propose that Mtss1 promotes Rac1 activation and actin recruitment...”
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