The biogenesis and function of nucleosome arrays

por Ashish Kumar Singh, Tamás Schauer, Lena Pfaller, Tobias Straub, Felix Mueller-Planitz
Publicado 2021

A general strategy for C(sp3)–H functionalization with nucleophiles using methyl radical as a hydrogen atom abstractor

por Isabelle Nathalie-Marie Leibler, Makeda A. Tekle-Smith, Abigail G. Doyle
Publicado 2021

Higher order genetic interactions switch cancer genes from two-hit to one-hit drivers

por Solip Park, Fran Supek, Ben Lehner
Publicado 2021

Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut

por Judith Behnsen, Hui Zhi, Allegra T. Aron, Vivekanandan Subramanian, William Santus, Michael H. Lee, Romana R. Gerner, Daniel Petras, Janet Z. Liu, Keith D. Green, Sarah L. Price, Jose Camacho, Hannah Hillman, Joshua Tjokrosurjo, Nicola P. Montaldo, Evelyn M. Hoover, Sean Treacy-Abarca, Benjamin A. Gilston, Eric P. Skaar, Walter J. Chazin, Sylvie Garneau-Tsodikova, Matthew B. Lawrenz, Robert D. Perry, Sean-Paul Nuccio, Pieter C. Dorrestein, Manuela Raffatellu
Publicado 2021

Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution

por Christina M. Termini, Amara Pang, Tiancheng Fang, Martina Roos, Vivian Y. Chang, Yurun Zhang, Nicollette J. Setiawan, Lia Signaevskaia, Michelle Li, Mindy M. Kim, Orel Tabibi, Paulina K. Lin, Joshua P. Sasine, Avradip Chatterjee, Ramachandran Murali, Heather A. Himburg, John P. Chute
Publicado 2021

Directed-evolution of translation system for efficient unnatural amino acids incorporation and generalizable synthetic auxotroph construction

por Hongxia Zhao, Wenlong Ding, Jia Zang, Yang Yang, Chao Liu, Linzhen Hu, Yulin Chen, Guanglong Liu, Yu Fang, Ying Yuan, Shixian Lin
Publicado 2021

Spatiotemporal dynamics of SETD5-containing NCoR–HDAC3 complex determines enhancer activation for adipogenesis

por Yoshihiro Matsumura, Ryo Ito, Ayumu Yajima, Rei Yamaguchi, Toshiya Tanaka, Takeshi Kawamura, Kenta Magoori, Yohei Abe, Aoi Uchida, Takeshi Yoneshiro, Hiroyuki Hirakawa, Ji Zhang, Makoto Arai, Chaoran Yang, Ge Yang, Hiroki Takahashi, Hitomi Fujihashi, Ryo Nakaki, Shogo Yamamoto, Satoshi Ota, Shuichi Tsutsumi, Shin-ichi Inoue, Hiroshi Kimura, Youichiro Wada, Tatsuhiko Kodama, Takeshi Inagaki, Timothy F. Osborne, Hiroyuki Aburatani, Koichi Node, Juro Sakai
Publicado 2021

Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs

por Nathalia Varejão, Jara Lascorz, Joan Codina-Fabra, Gemma Bellí, Helena Borràs-Gas, Jordi Torres-Rosell, David Reverter
Publicado 2021

Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma

por Georgia Zoumpoulidou, Carlos Alvarez-Mendoza, Caterina Mancusi, Ritika-Mahmuda Ahmed, Milly Denman, Christopher D. Steele, Maxime Tarabichi, Errin Roy, Lauren R. Davies, Jiten Manji, Camilla Cristalli, Katia Scotlandi, Nischalan Pillay, Sandra J. Strauss, Sibylle Mittnacht
Publicado 2021

Phase transitions in natural C-O-H-N-S fluid inclusions - implications for gas mixtures and the behavior of solid H2S at low temperatures

por Marta Sośnicka, Volker Lüders
Publicado 2021

WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells

por Linlin Wang, Hongyang Liu, Xiaofei Zhang, Eli Song, You Wang, Tao Xu, Zonghong Li
Publicado 2021

Mapping the serum proteome to neurological diseases using whole genome sequencing

por Grace Png, Andrei Barysenka, Linda Repetto, Pau Navarro, Xia Shen, Maik Pietzner, Eleanor Wheeler, Nicholas J. Wareham, Claudia Langenberg, Emmanouil Tsafantakis, Maria Karaleftheri, George Dedoussis, Anders Mälarstig, James F. Wilson, Arthur Gilly, Eleftheria Zeggini
Publicado 2021

Mounting, structure and autocleavage of a type VI secretion-associated Rhs polymorphic toxin

por Dukas Jurėnas, Leonardo Talachia Rosa, Martial Rey, Julia Chamot-Rooke, Rémi Fronzes, Eric Cascales
Publicado 2021

Inconsistencies in the specific nucleobase pairing motif prone to photodimerization in a MOF nanoreactor

por Pascale Clivio
Publicado 2021

Modulation of dopamine tone induces frequency shifts in cortico-basal ganglia beta oscillations

por L. Iskhakova, P. Rappel, M. Deffains, G. Fonar, O. Marmor, R. Paz, Z. Israel, R. Eitan, H. Bergman
Publicado 2021

Assessing costs of Indonesian fires and the benefits of restoring peatland

por L. Kiely, D. V. Spracklen, S. R. Arnold, E. Papargyropoulou, L. Conibear, C. Wiedinmyer, C. Knote, H. A. Adrianto
Publicado 2021

Individual differences in information-seeking

por Christopher. A. Kelly, Tali Sharot
Publicado 2021

Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides

por Jinzhu Zhang, Minghai Tang, Yujie Chen, Dan Ke, Jie Zhou, Xinyu Xu, Wenxian Yang, Jianxiong He, Haohao Dong, Yuquan Wei, James H. Naismith, Yi Lin, Xiaofeng Zhu, Wei Cheng
Publicado 2021

Neural nano-optics for high-quality thin lens imaging

por Ethan Tseng, Shane Colburn, James Whitehead, Luocheng Huang, Seung-Hwan Baek, Arka Majumdar, Felix Heide
Publicado 2021

A DAP5/eIF3d alternate mRNA translation mechanism promotes differentiation and immune suppression by human regulatory T cells

por Viviana Volta, Sandra Pérez-Baos, Columba de la Parra, Olga Katsara, Amanda Ernlund, Sophie Dornbaum, Robert J. Schneider
Publicado 2021