Network-based machine learning in colorectal and bladder organoid models predicts anti-cancer drug efficacy in patients

por JungHo Kong, Heetak Lee, Donghyo Kim, Seong Kyu Han, Doyeon Ha, Kunyoo Shin, Sanguk Kim
Publicado 2020

Visualizing catalyst heterogeneity by a  multifrequential oscillating reaction

por Yuri Suchorski, Martin Datler, Ivan Bespalov, Johannes Zeininger, Michael Stöger-Pollach, Johannes Bernardi, Henrik Grönbeck, Günther Rupprechter
Publicado 2018

Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts

por Emilie Abby, Sophie Tourpin, Jonathan Ribeiro, Katrin Daniel, Sébastien Messiaen, Delphine Moison, Justine Guerquin, Jean-Charles Gaillard, Jean Armengaud, Francina Langa, Attila Toth, Emmanuelle Martini, Gabriel Livera
Publicado 2016

C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition

por Ana Rita Lourenço, M. Guy Roukens, Danielle Seinstra, Cynthia L. Frederiks, Cornelieke E. Pals, Stephin J. Vervoort, Andreia S. Margarido, Jacco van Rheenen, Paul J. Coffer
Publicado 2020

SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling

por Thomas Strub, Flavia G. Ghiraldini, Saul Carcamo, Man Li, Aleksandra Wroblewska, Rajendra Singh, Matthew S. Goldberg, Dan Hasson, Zichen Wang, Stuart J. Gallagher, Peter Hersey, Avi Ma’ayan, Georgina V. Long, Richard A. Scolyer, Brian Brown, Bin Zheng, Emily Bernstein
Publicado 2018

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

por Joanna Ratajczak, Magali Joffraud, Samuel A. J. Trammell, Rosa Ras, Núria Canela, Marie Boutant, Sameer S. Kulkarni, Marcelo Rodrigues, Philip Redpath, Marie E. Migaud, Johan Auwerx, Oscar Yanes, Charles Brenner, Carles Cantó
Publicado 2016

Single reach plans in dorsal premotor cortex during a two-target task

por Brian M. Dekleva, Konrad P. Kording, Lee E. Miller
Publicado 2018

Anthropogenic effects are associated with a lower persistence of marine food webs

por Luis J. Gilarranz, Camilo Mora, Jordi Bascompte
Publicado 2016

Volcanic crystals as time capsules of eruption history

por Teresa Ubide, Balz S. Kamber
Publicado 2018

A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target

por Prashant K. Srivastava, Jonathan van Eyll, Patrice Godard, Manuela Mazzuferi, Andree Delahaye-Duriez, Juliette Van Steenwinckel, Pierre Gressens, Benedicte Danis, Catherine Vandenplas, Patrik Foerch, Karine Leclercq, Georges Mairet-Coello, Alvaro Cardenas, Frederic Vanclef, Liisi Laaniste, Isabelle Niespodziany, James Keaney, Julien Gasser, Gaelle Gillet, Kirill Shkura, Seon-Ah Chong, Jacques Behmoaras, Irena Kadiu, Enrico Petretto, Rafal M. Kaminski, Michael R. Johnson
Publicado 2018

Resource acquisition and reproductive strategies of tropical forest in response to the El Niño–Southern Oscillation

por Matteo Detto, S. Joseph Wright, Osvaldo Calderón, Helene C. Muller-Landau
Publicado 2018

Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes

por Nick A. Guagliardo, Peter M. Klein, Christina A. Gancayco, Adam Lu, Sining Leng, Rany R. Makarem, Chelsea Cho, Craig G. Rusin, David T. Breault, Paula Q. Barrett, Mark P. Beenhakker
Publicado 2020

Control of self-assembly pathways toward conglomerate and racemic supramolecular polymers

por Marius Wehner, Merle Insa Silja Röhr, Vladimir Stepanenko, Frank Würthner
Publicado 2020

Chromatin conformation analysis of primary patient tissue using a low input Hi-C method

por Noelia Díaz, Kai Kruse, Tabea Erdmann, Annette M. Staiger, German Ott, Georg Lenz, Juan M. Vaquerizas
Publicado 2018

Polaritonic molecular clock for all-optical ultrafast imaging of wavepacket dynamics without probe pulses

por R. E. F. Silva, Javier del Pino, Francisco J. García-Vidal, Johannes Feist
Publicado 2020

Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins

por Somnath Mukherjee, Satchal K. Erramilli, Mark Ammirati, Frances J. D. Alvarez, Kimberly F. Fennell, Michael D. Purdy, Blazej M. Skrobek, Katarzyna Radziwon, John Coukos, Yanyong Kang, Przemysław Dutka, Xiang Gao, Xiayang Qiu, Mark Yeager, H. Eric Xu, Seungil Han, Anthony A. Kossiakoff
Publicado 2020

Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cells

por Sicheng Fu, Kaixin He, Chenxi Tian, Hua Sun, Chenwen Zhu, Shiyu Bai, Jiwei Liu, Qielan Wu, Di Xie, Ting Yue, Zhuxia Shen, Qingqing Dai, Xiaojun Yu, Shu Zhu, Gang Liu, Rongbin Zhou, Shengzhong Duan, Zhigang Tian, Tao Xu, Hua Wang, Li Bai
Publicado 2020

LWD–TCP complex activates the morning gene CCA1 in Arabidopsis

por Jing-Fen Wu, Huang-Lung Tsai, Ignasius Joanito, Yi-Chen Wu, Chin-Wen Chang, Yi-Hang Li, Ying Wang, Jong Chan Hong, Jhih-Wei Chu, Chao-Ping Hsu, Shu-Hsing Wu
Publicado 2016

Large increase in global storm runoff extremes driven by climate and anthropogenic changes

por Jiabo Yin, Pierre Gentine, Sha Zhou, Sylvia C. Sullivan, Ren Wang, Yao Zhang, Shenglian Guo
Publicado 2018

BCL9 provides multi-cellular communication properties in colorectal cancer by interacting with paraspeckle proteins

por Meng Jiang, Yue Kang, Tomasz Sewastianik, Jiao Wang, Helen Tanton, Keith Alder, Peter Dennis, Yu Xin, Zhongqiu Wang, Ruiyang Liu, Mengyun Zhang, Ying Huang, Massimo Loda, Amitabh Srivastava, Runsheng Chen, Ming Liu, Ruben D. Carrasco
Publicado 2020