Systems approaches identify the consequences of monosomy in somatic human cells

por Narendra Kumar Chunduri, Paul Menges, Xiaoxiao Zhang, Angela Wieland, Vincent Leon Gotsmann, Balca R. Mardin, Christopher Buccitelli, Jan O. Korbel, Felix Willmund, Maik Kschischo, Markus Raeschle, Zuzana Storchova
Publicado 2021

Self-filtering narrowband high performance organic photodetectors enabled by manipulating localized Frenkel exciton dissociation

por Boming Xie, Ruihao Xie, Kai Zhang, Qingwu Yin, Zhicheng Hu, Gang Yu, Fei Huang, Yong Cao
Publicado 2020

ValLAI_Crop, a validation dataset for coarse-resolution satellite LAI products over Chinese cropland

por Bowen Song, Liangyun Liu, Shanshan Du, Xiao Zhang, Xidong Chen, Helin Zhang
Publicado 2021

Physical basis for the determination of lumen shape in a simple epithelium

por Claudia G. Vasquez, Vipul T. Vachharajani, Carlos Garzon-Coral, Alexander R. Dunn
Publicado 2021

Combining mechanistic and machine learning models for predictive engineering and optimization of tryptophan metabolism

por Jie Zhang, Søren D. Petersen, Tijana Radivojevic, Andrés Ramirez, Andrés Pérez-Manríquez, Eduardo Abeliuk, Benjamín J. Sánchez, Zak Costello, Yu Chen, Michael J. Fero, Hector Garcia Martin, Jens Nielsen, Jay D. Keasling, Michael K. Jensen
Publicado 2020

Leveraging the Cell Ontology to classify unseen cell types

por Sheng Wang, Angela Oliveira Pisco, Aaron McGeever, Maria Brbic, Marinka Zitnik, Spyros Darmanis, Jure Leskovec, Jim Karkanias, Russ B. Altman
Publicado 2021

A blueprint of the topology and mechanics of the human ovary for next-generation bioengineering and diagnosis

por Emna Ouni, Alexis Peaucelle, Kalina T. Haas, Olivier Van Kerk, Marie-Madeleine Dolmans, Timo Tuuri, Marjut Otala, Christiani A. Amorim
Publicado 2021

Extensive regulation of enzyme activity by phosphorylation in Escherichia coli

por Evgeniya Schastnaya, Zrinka Raguz Nakic, Christoph H. Gruber, Peter Francis Doubleday, Aarti Krishnan, Nathan I. Johns, Jimin Park, Harris H. Wang, Uwe Sauer
Publicado 2021

Unwinding of a DNA replication fork by a hexameric viral helicase

por Abid Javed, Balazs Major, Jonathan A. Stead, Cyril M. Sanders, Elena V. Orlova
Publicado 2021

Epistasis shapes the fitness landscape of an allosteric specificity switch

por Kyle K. Nishikawa, Nicholas Hoppe, Robert Smith, Craig Bingman, Srivatsan Raman
Publicado 2021

Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis

por Frank Penkava, Martin Del Castillo Velasco-Herrera, Matthew D. Young, Nicole Yager, Lilian N. Nwosu, Arthur G. Pratt, Alicia Lledo Lara, Charlotte Guzzo, Ash Maroof, Lira Mamanova, Suzanne Cole, Mirjana Efremova, Davide Simone, Andrew Filer, Chrysothemis C. Brown, Andrew L. Croxford, John D. Isaacs, Sarah Teichmann, Paul Bowness, Sam Behjati, M. Hussein Al-Mossawi
Publicado 2020

Thermal transport of helium-3 in a strongly confining channel

por D. Lotnyk, A. Eyal, N. Zhelev, T. S. Abhilash, E. N. Smith, M. Terilli, J. Wilson, E. Mueller, D. Einzel, J. Saunders, J. M. Parpia
Publicado 2020

A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer

por Panagiotis A. Konstantinopoulos, Alexandre André B. A. da Costa, Doga Gulhan, Elizabeth K. Lee, Su-Chun Cheng, Andrea E. Wahner Hendrickson, Bose Kochupurakkal, David L. Kolin, Elise C. Kohn, Joyce F. Liu, Elizabeth H. Stover, Jennifer Curtis, Nabihah Tayob, Madeline Polak, Dipanjan Chowdhury, Ursula A. Matulonis, Anniina Färkkilä, Alan D. D’Andrea, Geoffrey I. Shapiro
Publicado 2021

Massive methane fluxing from magma–sediment interaction in the end-Triassic Central Atlantic Magmatic Province

por Manfredo Capriolo, Andrea Marzoli, László E. Aradi, Michael R. Ackerson, Omar Bartoli, Sara Callegaro, Jacopo Dal Corso, Marcia Ernesto, Eleonora M. Gouvêa Vasconcellos, Angelo De Min, Robert J. Newton, Csaba Szabó
Publicado 2021

Emergent solidity of amorphous materials as a consequence of mechanical self-organisation

por Hua Tong, Shiladitya Sengupta, Hajime Tanaka
Publicado 2020

Transfer learning enables the molecular transformer to predict regio- and stereoselective reactions on carbohydrates

por Giorgio Pesciullesi, Philippe Schwaller, Teodoro Laino, Jean-Louis Reymond
Publicado 2020

A diploid assembly-based benchmark for variants in the major histocompatibility complex

por Chen-Shan Chin, Justin Wagner, Qiandong Zeng, Erik Garrison, Shilpa Garg, Arkarachai Fungtammasan, Mikko Rautiainen, Sergey Aganezov, Melanie Kirsche, Samantha Zarate, Michael C. Schatz, Chunlin Xiao, William J. Rowell, Charles Markello, Jesse Farek, Fritz J. Sedlazeck, Vikas Bansal, Byunggil Yoo, Neil Miller, Xin Zhou, Andrew Carroll, Alvaro Martinez Barrio, Marc Salit, Tobias Marschall, Alexander T. Dilthey, Justin M. Zook
Publicado 2020

Chiral gold nanoparticles enantioselectively rescue memory deficits in a mouse model of Alzheimer’s disease

por Ke Hou, Jing Zhao, Hui Wang, Bin Li, Kexin Li, Xinghua Shi, Kaiwei Wan, Jing Ai, Jiawei Lv, Dawei Wang, Qunxing Huang, Huayi Wang, Qin Cao, Shaoqin Liu, Zhiyong Tang
Publicado 2020

Reconstructing aspects of human embryogenesis with pluripotent stem cells

por Berna Sozen, Victoria Jorgensen, Bailey A. T. Weatherbee, Sisi Chen, Meng Zhu, Magdalena Zernicka-Goetz
Publicado 2021

Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization

por Rajesh Sharma, Kyoung-Jae Choi, My Diem Quan, Sonum Sharma, Banumathi Sankaran, Hyekyung Park, Anel LaGrone, Jean J. Kim, Kevin R. MacKenzie, Allan Chris M. Ferreon, Choel Kim, Josephine C. Ferreon
Publicado 2021