Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis

por Trinidad Montero-Melendez, Ai Nagano, Claude Chelala, Andrew Filer, Christopher D. Buckley, Mauro Perretti
Publicado 2020

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis

por Emmanuel Karouzakis, Karim Raza, Christoph Kolling, Christopher D. Buckley, Steffen Gay, Andrew Filer, Caroline Ospelt
Publicado 2018

Linking power Doppler ultrasound to the presence of th17 cells in the rheumatoid arthritis joint.

por Nicola J Gullick, Hayley G Evans, Leigh D Church, David M Jayaraj, Andrew Filer, Bruce W Kirkham, Leonie S Taams
Publicado 2010

Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions

por Mojca Frank-Bertoncelj, Michelle Trenkmann, Kerstin Klein, Emmanuel Karouzakis, Hubert Rehrauer, Anna Bratus, Christoph Kolling, Maria Armaka, Andrew Filer, Beat A. Michel, Renate E. Gay, Christopher D. Buckley, George Kollias, Steffen Gay, Caroline Ospelt
Publicado 2017

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis

por Yilin Wang, Aneesah Khan, Aristotelis Antonopoulos, Laura Bouché, Christopher D. Buckley, Andrew Filer, Karim Raza, Kun-Ping Li, Barbara Tolusso, Elisa Gremese, Mariola Kurowska-Stolarska, Stefano Alivernini, Anne Dell, Stuart M. Haslam, Miguel A. Pineda
Publicado 2021

Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis

por Frank Penkava, Martin Del Castillo Velasco-Herrera, Matthew D. Young, Nicole Yager, Lilian N. Nwosu, Arthur G. Pratt, Alicia Lledo Lara, Charlotte Guzzo, Ash Maroof, Lira Mamanova, Suzanne Cole, Mirjana Efremova, Davide Simone, Andrew Filer, Chrysothemis C. Brown, Andrew L. Croxford, John D. Isaacs, Sarah Teichmann, Paul Bowness, Sam Behjati, M. Hussein Al-Mossawi
Publicado 2020

Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans.

por Joanna E Cobb, Darren Plant, Edward Flynn, Meriem Tadjeddine, Philippe Dieudé, François Cornélis, Lisbeth Ärlestig, Solbritt Rantapää Dahlqvist, George Goulielmos, Dimitrios T Boumpas, Prodromos Sidiropoulos, Sophine B Krintel, Lykke M Ørnbjerg, Merete L Hetland, Lars Klareskog, Thomas Haeupl, Andrew Filer, Christopher D Buckley, Karim Raza, Torsten Witte, Reinhold E Schmidt, Oliver FitzGerald, Douglas Veale, Stephen Eyre, Jane Worthington
Publicado 2013

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

por Fumitaka Mizoguchi, Kamil Slowikowski, Kevin Wei, Jennifer L. Marshall, Deepak A. Rao, Sook Kyung Chang, Hung N. Nguyen, Erika H. Noss, Jason D. Turner, Brandon E. Earp, Philip E. Blazar, John Wright, Barry P. Simmons, Laura T. Donlin, George D. Kalliolias, Susan M. Goodman, Vivian P. Bykerk, Lionel B. Ivashkiv, James A. Lederer, Nir Hacohen, Peter A. Nigrovic, Andrew Filer, Christopher D. Buckley, Soumya Raychaudhuri, Michael B. Brenner
Publicado 2018