Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis

par Trinidad Montero-Melendez, Ai Nagano, Claude Chelala, Andrew Filer, Christopher D. Buckley, Mauro Perretti
Publié 2020

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis

par Emmanuel Karouzakis, Karim Raza, Christoph Kolling, Christopher D. Buckley, Steffen Gay, Andrew Filer, Caroline Ospelt
Publié 2018

A differential role for CD248 (Endosialin) in PDGF-mediated skeletal muscle angiogenesis.

par Amy J Naylor, Helen M McGettrick, William D Maynard, Philippa May, Francesca Barone, Adam P Croft, Stuart Egginton, Christopher D Buckley
Publié 2014

Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions

par Mojca Frank-Bertoncelj, Michelle Trenkmann, Kerstin Klein, Emmanuel Karouzakis, Hubert Rehrauer, Anna Bratus, Christoph Kolling, Maria Armaka, Andrew Filer, Beat A. Michel, Renate E. Gay, Christopher D. Buckley, George Kollias, Steffen Gay, Caroline Ospelt
Publié 2017

Lymphoid aggregates that resemble tertiary lymphoid organs define a specific pathological subset in metal-on-metal hip replacements.

par Saloni Mittal, Matthew Revell, Francesca Barone, Debbie L Hardie, Gulraj S Matharu, Alison J Davenport, Richard A Martin, Melissa Grant, Frederick Mosselmans, Paul Pynsent, Vaiyapuri P Sumathi, Owen Addison, Peter A Revell, Christopher D Buckley
Publié 2013

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis

par Yilin Wang, Aneesah Khan, Aristotelis Antonopoulos, Laura Bouché, Christopher D. Buckley, Andrew Filer, Karim Raza, Kun-Ping Li, Barbara Tolusso, Elisa Gremese, Mariola Kurowska-Stolarska, Stefano Alivernini, Anne Dell, Stuart M. Haslam, Miguel A. Pineda
Publié 2021

Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair

par Zhi Li, Tom Hodgkinson, Elizabeth J. Gothard, Soulmaz Boroumand, Rebecca Lamb, Ian Cummins, Priyanka Narang, Amy Sawtell, Jenny Coles, German Leonov, Andrea Reboldi, Christopher D. Buckley, Tom Cupedo, Christian Siebel, Ardeshir Bayat, Mark C. Coles, Carrie A. Ambler
Publié 2016

Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans.

par Joanna E Cobb, Darren Plant, Edward Flynn, Meriem Tadjeddine, Philippe Dieudé, François Cornélis, Lisbeth Ärlestig, Solbritt Rantapää Dahlqvist, George Goulielmos, Dimitrios T Boumpas, Prodromos Sidiropoulos, Sophine B Krintel, Lykke M Ørnbjerg, Merete L Hetland, Lars Klareskog, Thomas Haeupl, Andrew Filer, Christopher D Buckley, Karim Raza, Torsten Witte, Reinhold E Schmidt, Oliver FitzGerald, Douglas Veale, Stephen Eyre, Jane Worthington
Publié 2013

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

par Fumitaka Mizoguchi, Kamil Slowikowski, Kevin Wei, Jennifer L. Marshall, Deepak A. Rao, Sook Kyung Chang, Hung N. Nguyen, Erika H. Noss, Jason D. Turner, Brandon E. Earp, Philip E. Blazar, John Wright, Barry P. Simmons, Laura T. Donlin, George D. Kalliolias, Susan M. Goodman, Vivian P. Bykerk, Lionel B. Ivashkiv, James A. Lederer, Nir Hacohen, Peter A. Nigrovic, Andrew Filer, Christopher D. Buckley, Soumya Raychaudhuri, Michael B. Brenner
Publié 2018